Formaldehyde dismutase

formaldehyde dismutase
Identifiers
EC number 1.2.99.4
CAS number 85204-94-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a formaldehyde dismutase (EC 1.2.99.4) is an enzyme that catalyzes the chemical reaction

2 formaldehyde \rightleftharpoons formate + methanol

Hence, this enzyme has one substrate, formaldehyde, and two products, formate and methanol.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with other acceptors. The systematic name of this enzyme class is formaldehyde:formaldehyde oxidoreductase. Other names in common use include aldehyde dismutase, and cannizzanase.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2DPH.

References

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