Furafylline

Furafylline
Systematic (IUPAC) name
3-(furan-2-ylmethyl)-1,8-dimethyl-7H-purine-2,6-dione
Identifiers
CAS Number 80288-49-9 YesY
PubChem CID 3433
UNII C2087G0XX3 N
ChEMBL CHEMBL372638 N
Chemical data
Formula C12H12N4O3
Molar mass 260.25 g/mol
 NYesY (what is this?)  (verify)

Furafylline is a methylxanthine derivative that was introduced in hope of being a long-acting replacement for theophylline in the treatment of asthma.[1] It is an inhibitor of CYP1A2.[1]

References

  1. 1 2 Sesardic, D.; Boobis, A. R.; Murray, B. P.; Murray, S.; Segura, J.; De La Torre, R.; Davies, D. S. (1990). "Furafylline is a potent and selective inhibitor of cytochrome P450IA2 in man". British Journal of Clinical Pharmacology 29 (6): 651–663. doi:10.1111/j.1365-2125.1990.tb03686.x. PMC 1380167. PMID 2378786.


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