GALNT11

Polypeptide N-acetylgalactosaminyltransferase 11
Identifiers
Symbols	GALNT11 ; GALNAC-T11; GALNACT11
External IDs	OMIM: 615130 MGI: 2444392 HomoloGene: 11126 GeneCards: GALNT11 Gene
EC number	2.4.1.41
Gene ontology Molecular function • polypeptide N-acetylgalactosaminyltransferase activity • Notch binding • carbohydrate binding • metal ion binding Cellular component • Golgi membrane • integral component of membrane Biological process • protein O-linked glycosylation • Notch receptor processing • determination of left/right symmetry • regulation of Notch signaling pathway • O-glycan processing • protein O-linked glycosylation via threonine • post-translational protein modification • cellular protein metabolic process • cilium morphogenesis • Notch signaling involved in heart development Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	63917	231050
Ensembl	ENSG00000178234	ENSMUSG00000038072
UniProt	Q8NCW6	Q921L8
RefSeq (mRNA)	NM_001304514	NM_144908
RefSeq (protein)	NP_001291443	NP_659157
Location (UCSC)	Chr 7: 152.03 – 152.12 Mb	Chr 5: 25.22 – 25.27 Mb
PubMed search

Polypeptide N-acetylgalactosaminyltransferase 11 is an enzyme that in humans is encoded by the GALNT11 gene.^[1][2]

References

1. Schwientek T, Bennett EP, Flores C, Thacker J, Hollmann M, Reis CA, Behrens J, Mandel U, Keck B, Schafer MA, Haselmann K, Zubarev R, Roepstorff P, Burchell JM, Taylor-Papadimitriou J, Hollingsworth MA, Clausen H (Jun 2002). "Functional conservation of subfamilies of putative UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferases in Drosophila, Caenorhabditis elegans, and mammals. One subfamily composed of l(2)35Aa is essential in Drosophila". J Biol Chem 277 (25): 22623–38. doi:10.1074/jbc.M202684200. PMID 11925450.
2. "Entrez Gene: GALNT11 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)".

Further reading

• "Toward a complete human genome sequence.". Genome Res. 8 (11): 1097–108. 1999. doi:10.1101/gr.8.11.1097. PMID 9847074.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Scherer SW, Cheung J, MacDonald JR; et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
• Hillier LW, Fulton RS, Fulton LA; et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Brandenberger R, Wei H, Zhang S; et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Kimura K, Wakamatsu A, Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.