GC box

In molecular biology, a GC box is a distinct pattern of nucleotides found in the promoter region of some eukaryotic genes upstream of the TATA box and approximately 110 bases upstream from the transcription initiation site. It has a consensus sequence GGGCGG which is position dependent and orientation independent. The GC elements are bound by transcription factors and have similar functions to enhancers.[1]

References

  1. Klug WS, Cummings MR, Spencer CA, Palladina, MA (2009). Concepts of Genetics: Ninth Edition. San Francisco: Pearson Benjamin Cummings. pp. 463–464. ISBN 978-0-321-54098-0.
This article is issued from Wikipedia - version of the Wednesday, April 29, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.