GRIP2

Glutamate receptor interacting protein 2

PDB rendering based on 1v62.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbol GRIP2
External IDs MGI: 2681173 HomoloGene: 16327 GeneCards: GRIP2 Gene
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 80852 243547
Ensembl ENSG00000144596 ENSMUSG00000030098
UniProt Q9C0E4 E0CXE0
RefSeq (mRNA) NM_001080423 NM_001033353
RefSeq (protein) NP_001073892 NP_001152979
Location (UCSC) Chr 3:
14.49 – 14.54 Mb
Chr 6:
91.76 – 91.83 Mb
PubMed search

Glutamate receptor-interacting protein 2 is a protein that in humans is encoded by the GRIP2 gene.[1]

Interactions

GRIP2 has been shown to interact with liprin-alpha-1.[2][3]

References

  1. "Entrez Gene: GRIP2 glutamate receptor interacting protein 2".
  2. Ko J, Na M, Kim S, Lee JR, Kim E (Oct 2003). "Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins". J. Biol. Chem. 278 (43): 42377–85. doi:10.1074/jbc.M307561200. PMID 12923177.
  3. Ko J, Kim S, Valtschanoff JG, Shin H, Lee JR, Sheng M, Premont RT, Weinberg RJ, Kim E (Mar 2003). "Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting". J. Neurosci. 23 (5): 1667–77. PMID 12629171.

Further reading

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  • Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954. 
  • Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474. 
  • Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174. 
  • Srivastava S, Osten P, Vilim FS, Khatri L, Inman G, States B, Daly C, DeSouza S, Abagyan R, Valtschanoff JG, Weinberg RJ, Ziff EB (1998). "Novel anchorage of GluR2/3 to the postsynaptic density by the AMPA receptor-binding protein ABP". Neuron 21 (3): 581–91. doi:10.1016/S0896-6273(00)80568-1. PMID 9768844. 
  • Torres R, Firestein BL, Dong H, Staudinger J, Olson EN, Huganir RL, Bredt DS, Gale NW, Yancopoulos GD (1999). "PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands". Neuron 21 (6): 1453–63. doi:10.1016/S0896-6273(00)80663-7. PMID 9883737. 
  • Brückner K, Pablo Labrador J, Scheiffele P, Herb A, Seeburg PH, Klein R (1999). "EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains". Neuron 22 (3): 511–24. doi:10.1016/S0896-6273(00)80706-0. PMID 10197531. 
  • Nagase T, Ishikawa K, Kikuno R, Hirosawa M, Nomura N, Ohara O (2000). "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (5): 337–45. doi:10.1093/dnares/6.5.337. PMID 10574462. 
  • Ye B, Liao D, Zhang X, Zhang P, Dong H, Huganir RL (2000). "GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex". Neuron 26 (3): 603–17. doi:10.1016/S0896-6273(00)81198-8. PMID 10896157. 
  • Nagase T, Kikuno R, Hattori A, Kondo Y, Okumura K, Ohara O (2001). "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (6): 347–55. doi:10.1093/dnares/7.6.347. PMID 11214970. 
  • Hattori A, Okumura K, Nagase T, Kikuno R, Hirosawa M, Ohara O (2001). "Characterization of long cDNA clones from human adult spleen". DNA Res. 7 (6): 357–66. doi:10.1093/dnares/7.6.357. PMID 11214971. 
  • Lin SH, Arai AC, Wang Z, Nothacker HP, Civelli O (2001). "The carboxyl terminus of the prolactin-releasing peptide receptor interacts with PDZ domain proteins involved in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor clustering". Mol. Pharmacol. 60 (5): 916–23. PMID 11641419. 
  • Stegmüller J, Werner H, Nave KA, Trotter J (2003). "The proteoglycan NG2 is complexed with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by the PDZ glutamate receptor interaction protein (GRIP) in glial progenitor cells. Implications for glial-neuronal signaling". J. Biol. Chem. 278 (6): 3590–8. doi:10.1074/jbc.M210010200. PMID 12458226. 
  • Ko J, Na M, Kim S, Lee JR, Kim E (2004). "Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins". J. Biol. Chem. 278 (43): 42377–85. doi:10.1074/jbc.M307561200. PMID 12923177. 
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