Gapicomine

Gapicomine

Systematic (IUPAC) name
1-Pyridin-4-yl-N-(pyridin-4-ylmethyl)methanamine
Clinical data
Routes of administration	oral (tablet)
Legal status	off market (was used in EU countries)
Identifiers
CAS Number	1539-39-5
ATC code	none
PubChem	CID 68955
ChemSpider	62178
UNII	WWW0P95393
ChEMBL	CHEMBL2103958
Chemical data
Formula	C12H13N3
Molar mass	199.25 g/mol
SMILES n1ccc(cc1)CNCc2ccncc2
InChI InChI=1S/C12H13N3/c1-5-13-6-2-11(1)9-15-10-12-3-7-14-8-4-12/h1-8,15H,9-10H2 Key:AUQQZPGNRKTPSQ-UHFFFAOYSA-N
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Gapicomine (INN) is a coronary vasodilator. It has been withdrawn from the market in the countries it was used in.^[1]

Also, gapicomine is a major component in the drug Bicordin.^[2]

History

Gapicomine was discovered in 1970 by Polish chemist Stanisław Biniecki. It was first published about in an article of The Polish Journal of Medicine and Pharmacy describing the derivative drug Bicordin in 1974.^[3]

References

1. "Gapicomine Monograph, The Index Nominum". Retrieved 2008-03-31.
2. "Bicordin, PubChem". Retrieved 2008-03-31.
3. Samochowiec L, Wójcicki J, Gregorczyk K, Szmatloch E. (1974). "Bicordin--a new drug in the treatment of coronary heart disease.". Mater Med Pol. 6 (4): 298–300. PMID 4453155.