Gilean McVean
Gil McVean | |
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Born | Gilean Alistair Tristram McVean |
Institutions | |
Alma mater | University of Cambridge |
Doctoral advisor | Laurence Hurst[1][2][3] |
Other academic advisors | |
Doctoral students | |
Notable awards | Francis Crick Medal & Lecture (2010)[6] |
Gilean Alistair Tristram McVean is a professor of statistical genetics at the University of Oxford[7] and a fellow of Linacre College, Oxford. He is a member of the 1000 Genomes Project steering committee.[8]
Education
McVean completed his PhD in the Department of Genetics, at the University of Cambridge with Laurence Hurst[9][10] in 1997.[11]
Career and research
Following his PhD, McVean completed postdoctoral research at the University of Edinburgh under the supervision of Brian Charlesworth and Deborah Charlesworth.[12] From 2000-2004 he was a Royal Society University Research Fellow, in the Department of Statistics at Oxford, where he has also been a University lecturer in Mathematical Genetics since 2004.
His research[13] focuses on population genetics, statistics[14] and evolutionary biology including the International HapMap Project,[15][16] recombination rates in the human genome[17] and the 1000 Genomes Project.[18][19]
Honours and awards
- 2016 Elected Fellow of the Royal Society [20]
References
- ↑ Hurst, L.; McVean, G. (1996). "A difficult phase for introns-early. Molecular evolution". Current Biology 6 (5): 533–536. doi:10.1016/S0960-9822(02)00535-3. PMID 8805261.
- ↑ McVean, Gilean Alistair Tristram (1998). Adaptation and conflict : the differences between the sexes in mammalian genome evolution (PhD thesis). University of Cambridge. OCLC 894602716.
- ↑ "Students and post-docs past and present in the Hurst laboratory". University of Bath. Archived from the original on 2015-05-15.
- ↑ Moutsianas, Loukas (2011). Imputation aided analysis of the association between autoimmune diseases and the MHC (PhD thesis). University of Oxford. OCLC 820778016.
- ↑ http://www.stats.ox.ac.uk/~mcvean/group.html McVean group members
- ↑ http://royalsociety.org/awards/francis-crick-lecture/ Crick Lectures
- ↑ http://www.stats.ox.ac.uk/~mcvean/ McVean Group at the University of Oxford
- ↑ Gilean McVean publications from Europe PubMed Central
- ↑ McVean, G.T.; Hurst, L.D. (1997). "Evidence for a selectively favourable reduction in the mutation rate of the X chromosome". Nature 386 (6623): 388–392. doi:10.1038/386388a0. PMID 9121553.
- ↑ Hurst, L.D.; McVean, G.T. (1996). "... And scandalous symbionts". Nature 381 (6584): 650–651. doi:10.1038/381650a0. PMID 8649507.
- ↑ http://www.stats.ox.ac.uk/people/academic_staff/gilean_mcvean Gilean McVean Oxford University
- ↑ Charlesworth, D.; Charlesworth, B.; McVean, G. (2001). "Genome sequences and evolutionary biology, a two-way interaction". Trends in Ecology & Evolution 16 (5): 235–242. doi:10.1016/S0169-5347(01)02126-7. PMID 11301152.
- ↑ http://scholar.google.com/scholar?q=gilean+mcvean Gilean McVean in Google Scholar
- ↑ Reshef, D. N.; Reshef, Y. A.; Finucane, H. K.; Grossman, S. R.; McVean, G.; Turnbaugh, P. J.; Lander, E. S.; Mitzenmacher, M.; Sabeti, P. C. (2011). "Detecting Novel Associations in Large Data Sets". Science 334 (6062): 1518–1524. doi:10.1126/science.1205438. PMC 3325791. PMID 22174245.
- ↑ Frazer, K. A.; Frazer, D. G.; Ballinger, D. R.; Cox, D. A.; Hinds, L. L.; Stuve, R. A.; Gibbs, J. W.; Belmont, A.; Boudreau, P.; Hardenbol, S. M.; Leal, S.; Pasternak, D. A.; Wheeler, T. D.; Willis, F.; Yu, H.; Yang, C.; Zeng, Y.; Gao, H.; Hu, W.; Hu, C.; Li, W.; Lin, S.; Liu, H.; Pan, X.; Tang, J.; Wang, W.; Wang, J.; Yu, B.; Zhang, Q.; Zhang, H. (2007). "A second generation human haplotype map of over 3.1 million SNPs". Nature 449 (7164): 851–861. doi:10.1038/nature06258. PMC 2689609. PMID 17943122.
- ↑ Sabeti, Pardis C.; Varilly, Patrick; Fry, Ben; Lohmueller, Jason; Hostetter, Elizabeth; Cotsapas, Chris; Xie, Xiaohui; Byrne, Elizabeth H.; McCarroll, Steven A.; Gaudet, Rachelle; Schaffner, Stephen F.; Lander, Eric S.; The International HapMap Consortium; Frazer, Kelly A.; Ballinger, Dennis G.; Cox, David R.; Hinds, David A.; Stuve, Laura L.; Gibbs, Richard A.; Belmont, John W.; Boudreau, Andrew; Hardenbol, Paul; Leal, Suzanne M.; Pasternak, Shiran; Wheeler, David A.; Willis, Thomas D.; Yu, Fuli; Yang, Huanming; Zeng, Changqing Zeng; Gao, Yang (2007). "Genome-wide detection and characterization of positive selection in human populations". Nature 449 (7164): 913–918. doi:10.1038/nature06250. PMC 2687721. PMID 17943131.
- ↑ McVean, G. A. T.; Myers, S.; Hunt, S.; Deloukas, P.; Bentley, D.; Donnelly, P. (2004). "The Fine-Scale Structure of Recombination Rate Variation in the Human Genome". Science 304 (5670): 581–584. doi:10.1126/science.1092500. PMID 15105499.
- ↑ Danecek, P.; Auton, A.; Abecasis, G.; Albers, C. A.; Banks, E.; Depristo, M. A.; Handsaker, R.; Lunter, G.; Marth, G.; Sherry, S. T.; McVean, G.; Durbin, R.; 1000 Genomes Project Analysis Group (2011). "The Variant Call Format and VCFtools". Bioinformatics 27 (15): 2156–2158. doi:10.1093/bioinformatics/btr330. PMC 3137218. PMID 21653522.
- ↑ Hernandez, R. D.; Kelley, J. L.; Elyashiv, E.; Melton, S. C.; Auton, A.; McVean, G.; 1000 Genomes Project; Sella, G.; Przeworski, M. (2011). "Classic Selective Sweeps Were Rare in Recent Human Evolution". Science 331 (6019): 920–924. doi:10.1126/science.1198878. PMC 3669691. PMID 21330547.
- ↑ "Gilean McVean". Royal Society. Retrieved 1 May 2016.
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