Giles (bacteriophage)

Giles
Scientific classification
Order: Caudovirales
Family: Siphoviridae
Species: Giles

Giles is a bacteriophage that infects Mycobacterium smegmatis bacteria.[1] The genome of this phage is very different from that of other mycobacteriophages and is highly mosaic. More than half of its predicted genes are novel and are not seen in other species.[2][3]

References

  1. ↑ Morris, P; Marinelli, LJ; Jacobs-Sera, D; Hendrix, RW; Hatfull, GF (March 2008). "Genomic characterization of mycobacteriophage Giles: evidence for phage acquisition of host DNA by illegitimate recombination". Journal of Bacteriology 190 (6): 2172–82. doi:10.1128/JB.01657-07. PMC 2258872. PMID 18178732.
  2. ↑ Hatfull, GF; Jacobs-Sera, D; Lawrence, JG; Pope, WH; Russell, DA; Ko, CC; Weber, RJ; Patel, MC; Germane, KL; Edgar, RH; Hoyte, NN; Bowman, CA; Tantoco, AT; Paladin, EC; Myers, MS; Smith, AL; Grace, MS; Pham, TT; O'Brien, MB; Vogelsberger, AM; Hryckowian, AJ; Wynalek, JL; Donis-Keller, H; Bogel, MW; Peebles, CL; Cresawn, SG; Hendrix, RW (Mar 19, 2010). "Comparative genomic analysis of 60 Mycobacteriophage genomes: genome clustering, gene acquisition, and gene size". Journal of Molecular Biology 397 (1): 119–43. doi:10.1016/j.jmb.2010.01.011. PMC 2830324. PMID 20064525.
  3. ↑ Dedrick, Rebekah M.; Marinelli, Laura J.; Newton, Gerald L.; Pogliano, Kit; Pogliano, Joseph; Hatfull, Graham F. (May 2013). "Functional requirements for bacteriophage growth: gene essentiality and expression in mycobacteriophage Giles". Molecular Microbiology 88 (3): 577–589. doi:10.1111/mmi.12210. PMC 3641587. PMID 23560716.

External links


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