Glutamate dehydrogenase (NAD(P)+)

Glutamate dehydrogenase (NAD(P)+)
Identifiers
EC number 1.4.1.3
CAS number 2604152
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Glutamate dehydrogenase (NAD(P)+) (EC 1.4.1.3, glutamic dehydrogenase, glutamate dehydrogenase [NAD(P)+]) is an enzyme with systematic name L-glutamate:NAD(P)+ oxidoreductase (deaminating).[1][2][3] This enzyme catalyses the following chemical reaction

L-glutamate + H2O + NAD(P)+ \rightleftharpoons 2-oxoglutarate + NH3 + NAD(P)H + H+

References

  1. Olson, J.A. and Anfinsen, C.B. (1952). "The crystallization and characterization of L-glutamic acid dehydrogenase". J. Biol. Chem. 197: 67–79. PMID 12981035.
  2. Smith, E.L., Austen, B.M., Blumenthal, K.M. and Nyc, J.F. (1975). "Glutamate dehydrogenases". In Boyer, P.D. The Enzymes 11 (3rd ed.). New York: Academic Press. pp. 293–367.
  3. Strecker, H.J. (1953). "Glutamic dehydrogenase". Arch. Biochem. Biophys. 46: 128–140. PMID 13092953.

External links

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