Glycyrrhizol

Glycyrrhizol A

Names
IUPAC name 1-Methoxy-2,8-bis-(3-methyl-but-2-enyl)-6H-[1]benzofuro[3,2-c]chromene-3,9-diol
Identifiers
CAS Number	877373-00-7
ChEBI	CHEBI:65976
ChEMBL	ChEMBL522282
ChemSpider	9721048
Jmol interactive 3D	Image
PubChem	11546269
InChI InChI=1S/C26H28O5/c1-14(2)6-8-16-10-18-19-13-30-23-12-21(28)17(9-7-15(3)4)25(29-5)24(23)26(19)31-22(18)11-20(16)27/h6-7,10-12,27-28H,8-9,13H2,1-5H3 Key: CBPFOSMNDISZLV-UHFFFAOYSA-N InChI=1/C26H28O5/c1-14(2)6-8-16-10-18-19-13-30-23-12-21(28)17(9-7-15(3)4)25(29-5)24(23)26(19)31-22(18)11-20(16)27/h6-7,10-12,27-28H,8-9,13H2,1-5H3 Key: CBPFOSMNDISZLV-UHFFFAOYAJ
SMILES o2c1c(cc(c(O)c1)C\C=C(/C)C)c3c2c4c(OC)c(c(O)cc4OC3)C\C=C(/C)C
Properties
Chemical formula	C26H28O5
Molar mass	420.50 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Glycyrrhizol A is a prenylated pterocarpan, a derivative of isoflavonoids. It is a compound isolated from the root of the Chinese Licorice plant (Glycyrrhiza uralensis).

Recent studies by scientists from UCLA have suggested that these compounds have antibacterial properties.^[1] The strongest antibacterial activity was observed against Streptococcus mutans, an organism known to cause tooth decay in humans.

References

1. He J, Chen L, Shi W, Lu, Q-Y (2006). "Antibacterial Compounds from Glycyrrhiza uralensis". Journal of Natural Products 69 (1): 121–124. doi:10.1021/np058069d. PMID 16441081.