HMG
HMG may refer to:
- Heavy machine gun, a class of larger-caliber weapon
 - Her Majesty's Government, the government of the United Kingdom
 - High-mobility group, a group of proteins
 - HMG-CoA (3-hydroxy-3-methylglutaryl-coenzyme A)
 - Holland Media Groep, now RTL Nederland
 - Human menopausal gonadotrophin, a fertility drug
 - Human Molecular Genetics, a scientific journal
 - Southwestern Guiyang Miao language, spoken in China
 
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