Heart failure with preserved ejection fraction

Heart failure with preserved ejection fraction (HF/pEF) is commonly understood as manifestation of signs and symptoms of heart failure with an ejection fraction greater than 50%.[1] Roughly half of heart failure patients have reduced ejection fraction and half have preserved ejection fraction.[1]

HF/pEF is characterized by a decrease in left ventricular compliance, leading to increased pressure in the left ventricle. Increased left atrial size is often seen with HF/pEF as a result of the poor left ventricular function. There is an increased risk for congestive heart failure, atrial fibrillation, and pulmonary hypertension. Risk factors are hypertension, hyperlipidemia, diabetes, smoking, and obstructive sleep apnea. There is a query about how this rendering may describe diastolic heart failure.[2]

Randomized studies on HF/pEF patients have shown that exercise has a positive lusitropic effect on left ventricular diastolic function associated with improved exercise capacity.[3]

HF/pEF is best tested-for by analyzing diastolic function during exercise.[4]

See also

References

  1. 1 2 Owan TE, Hodge DO, Herges RM, Jacobsen SJ, Roger VL, Redfield MM (2006). "Trends in prevalence and outcome of heart failure with preserved ejection fraction". The New England Journal of Medicine 355 (3): 251–259. PMID 16855265.
  2. ↑ "Heart failure with preserved ejection fraction: is this diastolic heart failure?". Retrieved February 16, 2012.
  3. ↑ Gielen S, Laughlin MH, O'Conner C, Duncker DJ (2015). "Exercise training in patients with heart disease: review of beneficial effects and clinical recommendations" (PDF). Progress in Cardiovascular Diseases 57 (4): 347–355. doi:10.1016/j.pcad.2014.10.001. PMID 25459973.
  4. ↑ Erdei T, Aakhus S, Marino P, Paulus WJ, Smiseth OA, Fraser AG (2015). "Pathophysiological rationale and diagnostic targets for diastolic stress testing". Heart (journal) 101 (17): 1355–1360. doi:10.1136/heartjnl-2014-307040. PMID 26001845.

External links

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