Hemin
For the given name, see Hemin (given name).
Systematic (IUPAC) name | |
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Chloro[3,7,12,17-tetramethyl-8,13-divinylporphyrin-2,18-dipropanoato(2−)]iron(III) | |
Clinical data | |
AHFS/Drugs.com | Consumer Drug Information |
Pregnancy category |
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Routes of administration | Intravenous infusion |
Legal status | |
Legal status |
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Identifiers | |
CAS Number | 16009-13-5 |
ATC code | B06AB01 (WHO) |
PubChem | CID 5318002 |
ChemSpider | 21160444 |
UNII | 743LRP9S7N |
ChEMBL | CHEMBL1628226 |
Chemical data | |
Formula | C34H32ClFeN4O4 |
Molar mass | 651.94 g/mol |
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Hemin (trade name Panhematin) is an iron-containing porphyrin.[1] More specifically, it is protoporphyrin IX containing a ferric iron ion (heme B) with a chloride ligand.
It is used in the management of porphyria attacks, particularly in acute intermittent porphyria.
It is sometimes distinguished from hematin which has a hydroxide ligand in place of the chloride. However, the terms are sometimes equated.[2]
Hematin is considered the "X factor" required for the growth of Haemophilus influenzae.[3]
See also
References
- ↑ "hemin" at Dorland's Medical Dictionary
- ↑ "hematin" at Dorland's Medical Dictionary
- ↑ Sherris, John C.; Ryan, Kenneth J.; Ray, C. L. (2004). Sherris medical microbiology: an introduction to infectious diseases. New York: McGraw-Hill. p. 395. ISBN 0-8385-8529-9.
External links
- Information from the American Porphyria Foundation, including emergency delivery information
- Hemin at RxList
- Hemin at the US National Library of Medicine Medical Subject Headings (MeSH)
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