Histidine N-acetyltransferase

histidine N-acetyltransferase
Identifiers
EC number	2.3.1.33
CAS number	9027-59-2
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a histidine N-acetyltransferase (EC 2.3.1.33) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + L-histidine $\rightleftharpoons$ CoA + N-acetyl-L-histidine

Thus, the two substrates of this enzyme are acetyl-CoA and L-histidine, whereas its two products are CoA and N-acetyl-L-histidine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:L-histidine N-acetyltransferase. Other names in common use include acetylhistidine synthetase, and histidine acetyltransferase.

References

• Baslow MH (1966). "N -acetyl-L-histidine synthetase activity from the brain of the killifish". Brain. Res. 3 (2): 210–3. doi:10.1016/0006-8993(66)90082-5. PMID 5971525.