Hyalobarrier

Hyalobarrier is a substance to keep tissue apart post surgery and therefore prevent adhesions. It contains autocross-linked hyaluronan. Highly viscous due to condensation. Hyaluronan is present in cartilage and skin hence there is a natural metabolic pathway for it. This gel is used to separate organs and tissue after surgery. Scientific documentation so far covers the gynaecology speciality. IE Laparoscopic surgery, hysteroscopy/hysteroscopic surgery but also open surgery. According to data in a Cochrane collaboration review active action to prevent adhesions needs to be taken to a larger extent. The Cochrane report also states that the incidence of postsurgical adhesions is as high as 60 to 90%.[1] In a recent review by C Sutton (University of Surrey, Guilford UK), it is stated that Hyalobarrier is the only anti adhesive substance that has published data for intrauterine use.[2]

Additional information

References

  1. ↑ Ahmad G, Duffy JM, Farquhar C, et al. (2008). "Barrier agents for adhesion prevention after gynaecological surgery". Cochrane Database Syst Rev (2): CD000475. doi:10.1002/14651858.CD000475.pub2. PMID 18425865.
  2. ↑ Sutton C (2009). "Adhesions following surgery: pathogenesis and current experience with adhesion barriers". Surg Technol Int 18: 144–56. PMID 19579202.
This article is issued from Wikipedia - version of the Friday, April 29, 2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.