Hydroquinone 1,2-dioxygenase

Hydroquinone 1,2-dioxygenase
Identifiers
EC number	1.13.11.66
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Hydroquinone 1,2-dioxygenase (EC 1.13.11.66, hydroquinone dioxygenase) is an enzyme with systematic name benzene-1,4-diol:oxygen 1,2-oxidoreductase (decyclizing).^[1][2][3] This enzyme catalyses the following chemical reaction

benzene-1,4-diol + O₂ $\rightleftharpoons$ (2E,4Z)-4-hydroxy-6-oxohexa-2,4-dienoate

The enzyme is an extradiol-type dioxygenase. It belongs to the nonheme-iron(II)-dependent dioxygenase family.

References

1. Miyauchi, K., Adachi, Y., Nagata, Y. and Takagi, M. (1999). "Cloning and sequencing of a novel meta-cleavage dioxygenase gene whose product is involved in degradation of γ-hexachlorocyclohexane in Sphingomonas paucimobilis". J. Bacteriol. 181 (21): 6712–6719. PMC 94136. PMID 10542173.
2. Moonen, M.J., Synowsky, S.A., van den Berg, W.A., Westphal, A.H., Heck, A.J., van den Heuvel, R.H., Fraaije, M.W. and van Berkel, W.J. (2008). "Hydroquinone dioxygenase from pseudomonas fluorescens ACB: a novel member of the family of nonheme-iron(II)-dependent dioxygenases". J. Bacteriol. 190: 5199–5209. doi:10.1128/JB.01945-07. PMC 2493252. PMID 18502867.
3. Shen, W., Liu, W., Zhang, J., Tao, J., Deng, H., Cao, H. and Cui, Z. (2010). "Cloning and characterization of a gene cluster involved in the catabolism of p-nitrophenol from Pseudomonas putida DLL-E4". Bioresour. Technol. 101: 7516–7522. doi:10.1016/j.biortech.2010.04.052. PMID 20466541.

External links

• Hydroquinone 1,2-dioxygenase at the US National Library of Medicine Medical Subject Headings (MeSH)