Hypodermin C

Hypodermin C
Identifiers
EC number	3.4.21.49
CAS number	122191-36-0
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Hypodermin C (EC 3.4.21.49, Hypoderma collagenase) is an enzyme.^[1][2][3] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins including native collagen at -Ala bond leaving an N-terminal (75%) and a C-terminal (25%) fragment

This enzyme is isolated from the larva of a warble fly, Hypoderma lineatum.

References

1. Lecroisey, A., Boulard, C. and Keil, B. (1979). "Chemical and enzymatic characterization of the collagenase from the insect Hypoderma lineatum". Eur. J. Biochem. 101: 385–393. doi:10.1111/j.1432-1033.1979.tb19730.x. PMID 230030.
2. Lecroisey, A. and Keil, B. (1985). "Specificity of the collagenase from the insect Hypoderma lineatum". Eur. J. Biochem. 152: 123–130. doi:10.1111/j.1432-1033.1985.tb09171.x. PMID 2995028.
3. Lecroisey, A., Gilles, A.-M., De Wolf, A. and Keil, B. (1987). "Complete amino acid sequence of the collagenase from the insect Hypoderma lineatum". J. Biol. Chem. 262: 7546–7551. PMID 3034899.

External links

• Hypodermin C at the US National Library of Medicine Medical Subject Headings (MeSH)