IGHA2

Immunoglobulin heavy constant alpha 2 (A2m marker)
Identifiers
Symbol	IGHA2
External IDs	OMIM: 147000 GeneCards: IGHA2 Gene
Gene ontology Molecular function • antigen binding • immunoglobulin receptor binding Cellular component • extracellular region • extracellular space • extracellular exosome • monomeric IgA immunoglobulin complex • secretory IgA immunoglobulin complex • secretory dimeric IgA immunoglobulin complex • blood microparticle Biological process • retina homeostasis • glomerular filtration • receptor-mediated endocytosis • immune response • antibacterial humoral response • positive regulation of respiratory burst Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	3494	n/a
Ensembl	n/a	n/a
UniProt	P01877	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search		n/a

Ig alpha-2 chain C region is a protein that in humans is encoded by the IGHA2 gene.^[1]

References

1. "Entrez Gene: IGHA2 immunoglobulin heavy constant alpha 2 (A2m marker)".

Further reading

• Kerr MA (Oct 1990). "The structure and function of human IgA". The Biochemical Journal 271 (2): 285–96. PMC 1149552. PMID 2241915.
• Tsuzukida Y, Wang CC, Putnam FW (Mar 1979). "Structure of the A2m(1) allotype of human IgA--a recombinant molecule". Proceedings of the National Academy of Sciences of the United States of America 76 (3): 1104–8. doi:10.1073/pnas.76.3.1104. PMC 383197. PMID 286295.
• Toraño A, Putnam FW (Feb 1978). "Complete amino acid sequence of the alpha 2 heavy chain of a human IgA2 immunoglobulin of the A2m (2) allotype". Proceedings of the National Academy of Sciences of the United States of America 75 (2): 966–9. doi:10.1073/pnas.75.2.966. PMC 411380. PMID 416441.
• Ellison J, Buxbaum J, Hood L (1983). "Nucleotide sequence of a human immunoglobulin C gamma 4 gene". Dna 1 (1): 11–8. doi:10.1089/dna.1.1981.1.11. PMID 6299662.
• Ueda S, Nakai S, Nishida Y, Hisajima H, Honjo T (1984). "Long terminal repeat-like elements flank a human immunoglobulin epsilon pseudogene that lacks introns". The EMBO Journal 1 (12): 1539–44. PMC 553248. PMID 6327276.
• Hisajima H, Nishida Y, Nakai S, Takahashi N, Ueda S, Honjo T (May 1983). "Structure of the human immunoglobulin C epsilon 2 gene, a truncated pseudogene: implications for its evolutionary origin". Proceedings of the National Academy of Sciences of the United States of America 80 (10): 2995–9. doi:10.1073/pnas.80.10.2995. PMC 393960. PMID 6407005.
• Flanagan JG, Lefranc MP, Rabbitts TH (Mar 1984). "Mechanisms of divergence and convergence of the human immunoglobulin alpha 1 and alpha 2 constant region gene sequences". Cell 36 (3): 681–8. doi:10.1016/0092-8674(84)90348-9. PMID 6421489.
• Ellison J, Hood L (Mar 1982). "Linkage and sequence homology of two human immunoglobulin gamma heavy chain constant region genes". Proceedings of the National Academy of Sciences of the United States of America 79 (6): 1984–8. doi:10.1073/pnas.79.6.1984. PMC 346106. PMID 6804948.
• Flanagan JG, Rabbitts TH (Dec 1982). "Arrangement of human immunoglobulin heavy chain constant region genes implies evolutionary duplication of a segment containing gamma, epsilon and alpha genes". Nature 300 (5894): 709–13. doi:10.1038/300709a0. PMID 6817141.
• Bunkenborg J, Pilch BJ, Podtelejnikov AV, Wiśniewski JR (Feb 2004). "Screening for N-glycosylated proteins by liquid chromatography mass spectrometry". Proteomics 4 (2): 454–65. doi:10.1002/pmic.200300556. PMID 14760718.
• Kristiansen TZ, Bunkenborg J, Gronborg M, Molina H, Thuluvath PJ, Argani P, Goggins MG, Maitra A, Pandey A (Jul 2004). "A proteomic analysis of human bile". Molecular & Cellular Proteomics 3 (7): 715–28. doi:10.1074/mcp.M400015-MCP200. PMID 15084671.
• Ramachandran P, Boontheung P, Xie Y, Sondej M, Wong DT, Loo JA (Jun 2006). "Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry". Journal of Proteome Research 5 (6): 1493–503. doi:10.1021/pr050492k. PMID 16740002.
• Bernhard OK, Kapp EA, Simpson RJ (Mar 2007). "Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides". Journal of Proteome Research 6 (3): 987–95. doi:10.1021/pr0604559. PMID 17330941.