IL17RC
| Interleukin 17 receptor C | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | IL17RC ; CANDF9; IL17-RL; IL17RL | ||||||||||||
| External IDs | OMIM: 610925 MGI: 2159336 HomoloGene: 15894 GeneCards: IL17RC Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 84818 | 171095 | |||||||||||
| Ensembl | ENSG00000163702 | ENSMUSG00000030281 | |||||||||||
| UniProt | Q8NAC3 | Q8K4C2 | |||||||||||
| RefSeq (mRNA) | NM_001203263 | NM_134159 | |||||||||||
| RefSeq (protein) | NP_001190192 | NP_598920 | |||||||||||
| Location (UCSC) |
Chr 3: 9.92 – 9.93 Mb |
Chr 6: 113.47 – 113.48 Mb | |||||||||||
| PubMed search | |||||||||||||
Interleukin-17 receptor C is a protein that in humans is encoded by the IL17RC gene.[1][2]
This gene encodes a single-pass transmembrane protein that shares limited similarity with the interleukin-17 receptor. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only three have been determined to date.[2]
See also
References
- ↑ Haudenschild D, Moseley T, Rose L, Reddi AH (Feb 2002). "Soluble and transmembrane isoforms of novel interleukin-17 receptor-like protein by RNA splicing and expression in prostate cancer". J Biol Chem 277 (6): 4309–16. doi:10.1074/jbc.M109372200. PMID 11706037.
- 1 2 "Entrez Gene: IL17RC interleukin 17 receptor C".
Further reading
- Gerritsen ME, Tomlinson JE, Zlot C, et al. (2004). "Using gene expression profiling to identify the molecular basis of the synergistic actions of hepatocyte growth factor and vascular endothelial growth factor in human endothelial cells". Br. J. Pharmacol. 140 (4): 595–610. doi:10.1038/sj.bjp.0705494. PMC 1574080. PMID 14504135.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC 2286551. PMID 15340161.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Haudenschild DR, Curtiss SB, Moseley TA, Reddi AH (2006). "Generation of interleukin-17 receptor-like protein (IL-17RL) in prostate by alternative splicing of RNA". Prostate 66 (12): 1268–74. doi:10.1002/pros.20422. PMID 16688746.
- Toy D, Kugler D, Wolfson M, et al. (2006). "Cutting edge: interleukin 17 signals through a heteromeric receptor complex". J. Immunol. 177 (1): 36–9. doi:10.4049/jimmunol.177.1.36. PMID 16785495.
- Kuestner RE, Taft DW, Haran A, et al. (2007). "Identification of the IL-17 Receptor Related Molecule IL-17RC as the Receptor for IL-17F". J. Immunol. 179 (8): 5462–73. doi:10.4049/jimmunol.179.8.5462. PMC 2849293. PMID 17911633.
External links
- IL17RC protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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