IRS (disambiguation)

IRS is the United States Internal Revenue Service.

IRS may also refer to:

Medicine

• Indoor residual spraying, the spraying of insecticide to kill the mosquitoes that spread malaria
• Insulin receptor substrate, a protein family involved in the insulin signaling pathway (insulin response)
• Intergroup Rhabdomyosarcoma Study Group, about the cancer, rhabdomyosarcoma
• Immune reconstitution syndrome, or Immune reconstitution inflammatory syndrome

Economics

• Indian Revenue Service, of the Republic of India
• Interest rate swap
• International Retail Service, a service provided by the London Stock Exchange

Organisations

• I.R.S. Records
• Independence Republic of Sardinia, an independentist political party in Sardinia, Italy
• Institute of Regional Studies
• Leibniz Institute for Research on Society and Space, a research institute in Germany and part of the Leibniz Association

Transportation

• Independent rear suspension, a form of independent suspension, used in automobiles
• Industrial Railway Society, a UK railway society
• International Railway Standard, standards produced by the International Union of Railways
• Inertial reference system, more commonly known as an inertial navigation system
• International Railway Systems, a Romanian freight railroad car producer
• IRS Airlines, an airline of Nigeria

Other

• "I.R.S.", a song by Guns N' Roses featured on their album Chinese Democracy
• International Rules Series
• Irwin R. Schyster, often abbreviated I.R.S., a ring name of professional wrestler Mike Rotunda
• Indian Remote Sensing satellite
• Indian Readership Survey
• Information Retrieval System, in computer science
• Integrated reception system, for TV and radio signals
• Imperium Romanum Sacrum, the Latin name for the Holy Roman Empire
• IR$, a Franco-Belgian comics series telling the adventures of Larry Max, an IRS special agent
• Institutionalized Riot Systems