Inosine pranobex

Inosine pranobex
Names

IUPAC name 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one : 4-acetamidobenzoic acid : 1-(dimethylamino)propan-2-ol
Other names Isoprinosine; Methisoprinol
Identifiers
CAS Number	36703-88-5
ChemSpider	16736312
Jmol interactive 3D	Image
KEGG	D01995
PubChem	37510
InChI InChI=1/C10H12N4O5.C9H9NO3.C5H13NO/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18;1-6(11)10-8-4-2-7(3-5-8)9(12)13;1-5(7)4-6(2)3/h2-4,6-7,10,15-17H,1H2,(H,11,12,18);2-5H,1H3,(H,10,11)(H,12,13);5,7H,4H2,1-3H3/t4-,6-,7-,10-;;/m0../s1 Key: PBJNZCQJMWVIRT-MDQYBHOLBR
SMILES CN(C)CC(C)O.OC(=O)c1ccc(NC(C)=O)cc1.Oc3ncnc2c3ncn2[C@H]1O[C@@H](CO)[C@H](O)[C@@H]1O
Properties
Chemical formula	C₅₂H₇₈N₁₀O₁₇
Molar mass	1115.23 g/mol
Pharmacology
ATC code	J05AX05
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, and dimethylaminoisopropanol used as an antiviral drug. Inosine pranobex has no effect on viral particles itself. It acts as a immunostimulant, an analog of thymus hormones.^[1] It is most commonly used to treat the rare measles complication subacute sclerosing panencephalitis in conjunction with intrathecal interferon therapy.^[2]

References

↑ American Cancer Society. "Inosine Pranobex". Retrieved 31 July 2013.
↑ Campoli-Richards DM, Sorkin EM, Heel RC. (Nov 1986). "Inosine pranobex. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy". Drugs 32 (5): 383–424. doi:10.2165/00003495-198632050-00001.

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