Indazole

Indazole
Skeletal formula with numbering convention
Ball-and-stick model
Space-filling model
Names
IUPAC name
1H-indazole
Identifiers
271-44-3 YesY
ChEBI CHEBI:36670 YesY
ChEMBL ChEMBL86795 YesY
ChemSpider 8866 YesY
Jmol interactive 3D Image
PubChem 9221
Properties
C7H6N2
Molar mass 118.14 g/mol
Melting point 147 to 149 °C (297 to 300 °F; 420 to 422 K)
Boiling point 270 °C (518 °F; 543 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Indazole, also called isoindazole, is a heterocyclic aromatic organic compound. This bicyclic compound consists of the fusion of benzene and pyrazole.

Indazole derivatives display a broad variety of biological activities.

Indazoles are rare in nature. The alkaloids nigellicine, nigeglanine, and nigellidine are indazoles. Nigellicine was isolated from the widely distributed plant Nigella sativa L. (black cumin). Nigeglanine was isolated from extracts of Nigella glandulifera.

The Davis–Beirut reaction can generate 2H-indazoles.

Some derivatives

indazole-3-carboxylic acid
Having a carboxylic acid group on carbon 3. Can be further modified to lonidamine.

See also

References

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