Inogatran

Inogatran
Names

IUPAC name 2-{[(2R)-1-[(2S)-2-[(4-carbamimidamidobutyl)carbamoyl]piperidin-1-yl]-3-cyclohexyl-1-oxopropan-2-yl]amino}acetic acid
Other names Inogatran
Identifiers
ChEMBL	ChEMBL114715
ChemSpider	59397
Jmol interactive 3D	Image
UNII	428409I84L^Y
InChI InChI=1S/C21H38N6O4/c22-21(23)25-11-6-10-24-19(30)17-9-4-5-12-27(17)20(31)16(26-14-18(28)29)13-15-7-2-1-3-8-15/h15-17,26H,1-14H2,(H,24,30)(H,28,29)(H4,22,23,25)/t16-,17+/m1/s1 Key: CDPROXZBMHOBTQ-SJORKVTESA-N InChI=1/C21H38N6O4/c22-21(23)25-11-6-10-24-19(30)17-9-4-5-12-27(17)20(31)16(26-14-18(28)29)13-15-7-2-1-3-8-15/h15-17,26H,1-14H2,(H,24,30)(H,28,29)(H4,22,23,25)/t16-,17+/m1/s1 Key: CDPROXZBMHOBTQ-SJORKVTEBV
SMILES NC(=N)NCCCCNC(=O)[C@@H]1CCCCN1C(=O)[C@@H](CC1CCCCC1)NCC(O)=O
Properties
Chemical formula	C21 H38 N6 O4
Molar mass	438.6 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Inogatran is a low molecular weight peptidomimetic thrombin inhibitor. Inogatran was developed for the potential treatment of arterial and venous thrombotic diseases^[1]

References

↑ Teger-Nilsson, Ann-Catrine; Ruth Bylund; David Gustafsson; Erika Gyzander; Ulf Eriksson (1997). "IN VITRO EFFECTS OF INOGATRAN, A SELECTIVE LOW MOLECULAR WEIGHT THROMBIN INHIBITOR". Thrombosis Research 85 (2): 133–145. doi:10.1016/s0049-3848(96)00230-7.

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