Inosine pranobex

Inosine pranobex
Names
IUPAC name
9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one : 4-acetamidobenzoic acid : 1-(dimethylamino)propan-2-ol
Other names
Isoprinosine; Methisoprinol
Identifiers
36703-88-5
ChemSpider 16736312
Jmol interactive 3D Image
KEGG D01995
PubChem 37510
Properties
C52H78N10O17
Molar mass 1115.23 g/mol
Pharmacology
ATC code J05AX05
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, and dimethylaminoisopropanol used as an antiviral drug. Inosine pranobex has no effect on viral particles itself. It acts as a immunostimulant, an analog of thymus hormones.[1] It is most commonly used to treat the rare measles complication subacute sclerosing panencephalitis in conjunction with intrathecal interferon therapy.[2]

References

  1. American Cancer Society. "Inosine Pranobex". Retrieved 31 July 2013.
  2. Campoli-Richards DM, Sorkin EM, Heel RC. (Nov 1986). "Inosine pranobex. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy". Drugs 32 (5): 383–424. doi:10.2165/00003495-198632050-00001.


This article is issued from Wikipedia - version of the Sunday, March 20, 2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.