Isofuran

Isofurans are nonclassic eicosanoids formed nonenzymatically by free radical mediated peroxidation of arachidonic acid. The isofurans are similar to the isoprostanes and are formed under similar conditions, but contain a substituted tetrahydrofuran ring. The concentration of oxygen affects this process; at elevated oxygen concentrations, the formation of isofurans is favored whereas the formation of isoprostanes is disfavored.[1]

References

  1. Roberts, LJ 2nd and Fessel, JP (Mar 2004). "The biochemistry of the isoprostane, neuroprostane, and isofuran pathways of lipid peroxidation.". Chem Phys Lipids 128 ((1–2)): 173–86. doi:10.1111/j.1750-3639.2005.tb00511.x. PMID 15037162.


This article is issued from Wikipedia - version of the Thursday, April 17, 2014. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.