Isomaltulose synthase

This enzyme belongs to the family of isomerases, specifically those intramolecular transferases transferring other groups. The systematic name of this enzyme class is sucrose glucosylmutase. Other names in common use include isomaltulose synthetase, sucrose alpha-glucosyltransferase, and trehalulose synthase.

Structural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1M53, 1ZJA, 1ZJB, 2PWD, 2PWE, 2PWF, and 2PWG.

References

Cheetham PS (1984). "The extraction and mechanism of a novel isomaltulose-synthesizing enzyme from Erwinia rhapontici". Biochem. J. 220 (1): 213–20. PMC 1153612. PMID 6743261.
Cheetham PSJ, Imber CE and Isherwood J (1982). "The formation of isomaltulose by immobilized Erwinia rhapontici". Nature 299 (5884): 628–631. doi:10.1038/299628a0.

Isomerase: mutases (EC 5.4)

5.4.1 Acyl Groups	Lysolecithin acylmutase Precorrin-8X methylmutase

5.4.2 Phosphomutases	Phosphoglycerate mutase Bisphosphoglycerate mutase Phosphoglucomutase Phosphomannomutase PMM1 PMM2

5.4.99 Other groups	Methylmalonyl-CoA mutase Lanosterol synthase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

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