KAZALD1

Kazal-type serine peptidase inhibitor domain 1
Identifiers
Symbols	KAZALD1 ; BONO1; FKSG28; FKSG40; IGFBP-rP10
External IDs	OMIM: 609208 MGI: 2147606 HomoloGene: 12799 GeneCards: KAZALD1 Gene
Gene ontology Molecular function • insulin-like growth factor binding Cellular component • interstitial matrix Biological process • ossification • regulation of cell growth • multicellular organismal development • cell differentiation • extracellular matrix organization Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	81621	107250
Ensembl	ENSG00000107821	ENSMUSG00000025213
UniProt	Q96I82	Q8BJ66
RefSeq (mRNA)	NM_030929	NM_178929
RefSeq (protein)	NP_112191	NP_849260
Location (UCSC)	Chr 10: 101.06 – 101.07 Mb	Chr 19: 45.08 – 45.08 Mb
PubMed search

Kazal-type serine protease inhibitor domain-containing protein 1 is an enzyme that in humans is encoded by the KAZALD1 gene.^[1][2]

References

1. Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A (Oct 2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
2. "Entrez Gene: KAZALD1 Kazal-type serine peptidase inhibitor domain 1".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
• James MJ, Järvinen E, Thesleff I (2005). "Bono1: a gene associated with regions of deposition of bone and dentine". Gene Expr. Patterns 4 (5): 595–9. doi:10.1016/j.modgep.2004.01.013. PMID 15261838.
• Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC 2286551. PMID 15340161.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Shibata Y, Tsukazaki T, Hirata K, et al. (2005). "Role of a new member of IGFBP superfamily, IGFBP-rP10, in proliferation and differentiation of osteoblastic cells". Biochem. Biophys. Res. Commun. 325 (4): 1194–200. doi:10.1016/j.bbrc.2004.10.157. PMID 15555553.