Karen Avraham

Prof. Karen B. Avraham
Born 1962
Quebec, Canada
Residence Tel Aviv, Israel
Nationality US/Israel
Fields Genetics, Hearing Impairment
Institutions Tel Aviv University (Tel Aviv, Israel)
Alma mater Weizmann Institute (Rehovot, Israel), NCI-NIH (Maryland, USA)
Known for Human Genetics, Deafness, Israeli-Palestinian Scientific Cooperation

Karen B. Avraham (born in 1962) is an American-Israeli human geneticist. She is a full professor at Tel Aviv University, and the current Vice Dean of the Sackler Faculty of Medicine. Her laboratory is in the Department of Human Molecular Genetics and Biochemistry. She is currently President of the Israel Society for Auditory Research (ISAR, http://isar-society.org), President of the Federation of Israel Societies for Experimental Biology (FISEB/ILANIT, http://www.fiseb.org/) and a board member of the I-CORE: Gene Regulation in Complex Human Disease (http://www.icore-human-disease.org). Karen Avraham is Council member of the European Molecular Biology Organization (EMBO, http://www.embo.org/), Chair of the Scientific Committee of Agir Pour L’Audition (Acting for Hearing, http://www.agirpourlaudition.org/en/) in France, Council member of the Human Genome Organization (HUGO, http://hugo-international.org/), an elected member of the International Collegium Oto-Rhino-Laryngologicum Amicitiae Sacrum (CORLAS, http://www.corlas.org/), and past President of the Association for Research in Otolaryngology (ARO, http://www.aro.org/) and the Genetic Society of Israel (GSI, http://www.genetics-il.org). She is Associate Editor of the journals European Journal of Human Genetics, EMBO Molecular Medicine and Mammalian Genome.

Born in Canada, Karen Avraham moved to the US at a young age. She received her B.A. degree in Biology from Washington University, St. Louis, Missouri, U.S., her Ph.D. from the Weizmann Institute of Science, Rehovot, Israel, under the supervision of Prof. Yoram Groner, and her post-doctoral training at the National Cancer Institute, Frederick, MD, U.S., under the supervision of Dr. Nancy Jenkins and Dr. Neal Copeland.

Karen Avraham’s research has centered on the discovery of disease genes, focusing on hereditary hearing loss. Her team takes a comprehensive approach to study the molecular basis of hearing loss, using genetic, developmental, biochemical, cellular and bioinformatic tools. She leads the effort in exome sequencing for the discovery of disease genes to identify mutations that are relevant for the hearing-impaired population. Her group has demonstrated that microRNAs are essential for development and function of inner ear hair cells in vertebrates.

Karen Avraham has been awarded the Sir Bernard Katz Prize from the Humboldt Foundation (Germany), the Bruno Memorial Prize from the Rothschild Foundation and the Teva Prize for Groundbreaking Research in the Field of Rare Diseases. Funding in her laboratory includes from the National Institutes of Health, European Commission, Human Frontiers, I-CORE, Israel Science Foundation and the US-Israel Binational Science Foundation.

Thirty-nine students have been awarded their M.Sc. or Ph.D. under Prof. Avraham's supervision and 35 other students, physicians and post docs have trained in her lab. She is an author on 98 peer-reviewed manuscripts and 51 reviews and chapters.[1]

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