L-2-amino-4-chloropent-4-enoate dehydrochlorinase

L-2-amino-4-chloropent-4-enoate dehydrochlorinase
Identifiers
EC number	4.5.1.4
CAS number	113066-37-8
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a L-2-amino-4-chloropent-4-enoate dehydrochlorinase (EC 4.5.1.4), an enzyme, catalyzes the chemical reaction.

L-2-amino-4-chloropent-4-enoate + H₂O $\rightleftharpoons$ 2-oxopent-4-enoate + chloride + NH₃

Thus, the two substrates of this enzyme are L-2-amino-4-chloropent-4-enoate and H₂O, whereas its 3 products are 2-oxopent-4-enoate, chloride, and NH₃.

This enzyme belongs to the family of lyases, specifically the class of carbon-halide lyases. The systematic name of this enzyme class is L-2-amino-4-chloropent-4-enoate chloride-lyase (adding H₂O deaminating; 2-oxopent-4-enoate-forming). Other names in common use include L-2-amino-4-chloro-4-pentenoate dehalogenase, and L-2-amino-4-chloropent-4-enoate chloride-lyase (deaminating).

References

• Moriguchi M, Hoshino S and Hatanaka S-I (1987). "Dehalogenation and deamination of l-2-amino-4-chloro-4-pentenoic acid by Proteus mirabilis". Agric. Biol. Chem. 51: 3295. doi:10.1271/bbb1961.51.3295.