L-threo-3-Methylaspartate

L-threo-3-Methylaspartate
L-threo-3-methylaspartate
Names
IUPAC name
(2S,3S)-2-Amino-3-methylbutanedioic acid
Other names
L-threo-3-Methylaspartate; 3-Methylaspartic acid
Identifiers
6061-13-8
ChEBI CHEBI:47980
ChemSpider 389071
Jmol interactive 3D Image
KEGG C03618
PubChem 440064
Properties
C5H9NO4
Molar mass 147.13 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

L-threo-3-Methylaspartate is an unusual amino acid formed by glutamate mutase and can be metabolised by methylaspartate ammonia-lyase. It is found in the structures of the antibiotics friulimicin[1] and vicenistatin[1] and in carbon metabolism of haloarchaea (Methylaspartate cycle).[2]

References

  1. 1 2 Ogasawara, Y.; Kakinuma, K.; Eguchi, T. (2005). "Involvement of Glutamate Mutase in the Biosynthesis of the Unique Starter Unit of the Macrolactam Polyketide Antibiotic Vicenistatin". The Journal of Antibiotics 58 (7): 468–72. doi:10.1038/ja.2005.62. PMID 16161486.
  2. Khomyakova, M.; Bukmez, O.; Thomas, L. K.; Erb, T. J.; Berg, I. A. (2011). "A Methylaspartate Cycle in Haloarchaea". Science 331 (6015): 334–7. doi:10.1126/science.1196544. PMID 21252347.
This article is issued from Wikipedia - version of the Friday, September 04, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.