Layilin
Layilin | |||||||||||
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Identifiers | |||||||||||
Symbols | LAYN [] | ||||||||||
External IDs | HomoloGene: 18716 GeneCards: LAYN Gene | ||||||||||
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Orthologs | |||||||||||
Species | Human | Mouse | |||||||||
Entrez | 143903 | 244864 | |||||||||
Ensembl | ENSG00000204381 | ENSMUSG00000060594 | |||||||||
UniProt | Q6UX15 | Q8C351 | |||||||||
RefSeq (mRNA) | NM_001258390 | NM_001033534 | |||||||||
RefSeq (protein) | NP_001245319 | NP_001028706 | |||||||||
Location (UCSC) |
Chr 11: 111.54 – 111.56 Mb |
Chr 9: 51.06 – 51.08 Mb | |||||||||
PubMed search | |||||||||||
Layilin is a protein that in humans is encoded by the LAYN gene.[1]
References
Further reading
- Bono P, Rubin K, Higgins JM, Hynes RO (2001). "Layilin, a novel integral membrane protein, is a hyaluronan receptor". Mol. Biol. Cell 12 (4): 891–900. doi:10.1091/mbc.12.4.891. PMC 32274. PMID 11294894.
- Borowsky ML, Hynes RO (1998). "Layilin, a novel talin-binding transmembrane protein homologous with C-type lectins, is localized in membrane ruffles". J. Cell Biol. 143 (2): 429–42. doi:10.1083/jcb.143.2.429. PMC 2132847. PMID 9786953.
- Forteza RM, Casalino-Matsuda SM, Falcon NS, Valencia Gattas M, Monzon ME (2012). "Hyaluronan and layilin mediate loss of airway epithelial barrier function induced by cigarette smoke by decreasing E-cadherin". J. Biol. Chem. 287 (50): 42288–98. doi:10.1074/jbc.M112.387795. PMC 3516772. PMID 23048036.
- Bono P, Cordero E, Johnson K, Borowsky M, Ramesh V, Jacks T, Hynes RO (2005). "Layilin, a cell surface hyaluronan receptor, interacts with merlin and radixin". Exp. Cell Res. 308 (1): 177–87. doi:10.1016/j.yexcr.2005.04.017. PMID 15913605.
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