LINE1
LINE1 (also L1 and LINE-1) are transposable elements in the DNA of some organisms and belong to the group of Long interspersed nuclear elements (LINEs). L1 comprise approximately 17% of the human genome.[1]
The majority of L1 in the human genome are inactive, however some retained the ability to retrotranspose.[2]
See also
- L1Base, a database of functional annotations & predictions of active LINE1 elements
References
- ↑ International Human Genome Sequencing Consortium (Feb 2001). "Initial sequencing and analysis of the human genome". Nature 409 (6822): 860–921. doi:10.1038/35057062. PMID 11237011.
- ↑ Ostertag, Eric M.; Kazazian Jr, Haig H. (December 2001). "Biology of Mammalian L1 Retrotransposons". Annual Review of Genetics 35 (1): 501–538. doi:10.1146/annurev.genet.35.102401.091032.
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