Lipozene

Lipozene is a brand name dietary supplement sold by Obesity Research Institute, LLC. The primary ingredient in Lipozene is glucomannan.

Usage

Clinical trials examining the use of glucomannan for weight loss have produced mixed results.[1][2] A 2014 systematic review and meta-analysis of clinical trials failed to show that glucomannan supplementation generated statistically significant weight loss.[3] Obesity Research Foundation, LLC was fined $1.5 million by the Federal Trade Commission in 2005 for misleading statements about weight-loss results from a similar glucomannan-containing product.[4]

Ingredient

Lipozene contains a single ingredient, glucomannan, a water-soluble, fermentable dietary fiber extracted from the tuber or root of the elephant yam, also known as Konjac (Amorphophallus konjac or Amorphophallus rivieri).[5]

Adverse events

Adverse events include abdominal discomfort, diarrhea, and constipation.[3]

References

  1. ↑ Salas-Salvadó J, Farrés X, Luque X, Narejos S, Borrell M, Basora J, Anguera A, Torres F, Bulló M, Balanza R (2008). "Effect of two doses of a mixture of soluble fibres on body weight and metabolic variables in overweight or obese patients: a randomised trial.". Br J Nutr 99 (6): 1380–7. doi:10.1017/S0007114507868528. PMID 18031592.
  2. ↑ Keithley,J., Swanson, B., Mikolaitis, M., DeMeo, J., Zeller, L., Fogg, Adamji, J. 2013. Safety and Efficacy of Glucomannan for Weight Loss in Overweight and Moderately Obese Adults. J Obes. 2013; 2013: 610908
  3. 1 2 Onakpoya I, Posadzki P, Ernst E (February 2014). "The efficacy of glucomannan supplementation in overweight and obesity: a systematic review and meta-analysis of randomized clinical trials". Journal of the American College of Nutrition 33 (1): 70–8. doi:10.1080/07315724.2014.870013. PMID 24533610.
  4. ↑ http://www.ftc.gov/news-events/press-releases/2005/06/ftc-settles-claims-marketers-fiberthin-and-propolene
  5. ↑ Keithley,J., Swanson, B., Mikolaitis, M., DeMeo, J., Zeller, L., Fogg, Adamji, J. 2013. Safety and Efficacy of Glucomannan for Weight Loss in Overweight and Moderately Obese Adults. J Obes. 2013; 2013: 610908

External links

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