List of U.S. Highways in South Carolina

U.S. Highways of South Carolina
Highway marker for U.S. Highway 76
System information
Maintained by SCDOT
Formed:	November 11, 1926 (1926-11-11)^[1]
Highway names
US Routes:	U.S. Highway nn (US nn)
System links
South Carolina Highways Interstate U.S. State Scenic

There are 23 U.S. Highways that exist entirely or partially in the U.S. state of South Carolina. In South Carolina, all U.S. Highways are maintained by the South Carolina Department of Transportation (SCDOT).

U.S. Highways

Route	Southern or western terminus	Northern or eastern terminus	mi	km	Established	Deleted	Description
001 US 1	Georgia state line at North Augusta	North Carolina state line near Wallace	170.1	273.7	1926	—	Travels north-south along the sandhills region; connecting the cities of North Augusta, Aiken, Columbia, and Camden. South of Camden, it parallels with I-20.
015 US 15	Walterboro	North Carolina state line at McColl	158.6	255.2	1935	—	Travels north-south, connecting the cities of Walterboro, Sumter, and Bennettsville.
017 US 17	Georgia state line near Limehouse	North Carolina state line near Little River	221.0	355.7	1927	—	Travels north-south along the coastal plain area, connecting the cities of Hardeeville, Charleston, Georgetown, and Myrtle Beach.
021 US 21	Hunting Island State Park	North Carolina state line near Little River	232.2	373.7	1926	—	Travels north-south, connecting the cities of Beaufort, Orangeburg, Columbia, and Rock Hill. North of Columbia, it parallels with I-77.
025 US 25	Georgia state line in North Augusta	North Carolina state line near Travelers Rest	140.3	225.8	1926	—	Travels north-south in the western part of the state, connecting the cities of North Augusta, Greenwood, and Greenville.
029 US 29	Georgia state line near Holland Store	North Carolina state line at Blacksburg	109.1	175.6	1927	—	Travels north-south in the Upstate area, parallel to I-85. It connects the cities of Anderson, Greenville, and Spartanburg.
052 US 52	Charleston	North Carolina state line near Cheraw	161.0	259.1	1980s	—	Travels north-south, connecting the cities of Charleston, Lake City, Florence, and Darlington.
076 US 76	Georgia state line near Westminster	North Carolina state line near Nichols	297.9	479.4	1926	—	Longest US Highway in the state, going east-west; it connects the cities Anderson, Columbia, Sumter, and Florence.
078 US 78	Georgia state line near North Augusta	Charleston	141.0	226.9	1926	—	Travels east-west, connecting the cities of North Augusta, Aiken, Bamberg, and Charleston.
117 US 117	Conway	North Carolina state line near Little River	45.0	72.4	1932	1935	Replaced by US 501 and US 17.
123 US 123	Georgia state line near Westminster	Greenville	57.4	92.4	1968	—	Travels north-south in the Upstate area, connecting the cities of Westminster and Greenville.
176 US 176	North Carolina state line near Landrum	Goose Creek	218.7	352.0	1926	—	Travels east-west, parallel to I-26. It connects the cities of Spartanburg, Union, and Columbia.
178 US 178	Ridgeville	North Carolina state line near Rocky Bottom	232.7	374.5	1932	—	Travels east-west, connecting the cities of Anderson, Greenwood, and Orangeburg.
217 US 217	Pee Dee	North Carolina state line near Dillon	24.4	39.3	1927	1932	Replaced by US 301.
221 US 221	Georgia state line near Clarks Hill	North Carolina state line at Chesnee	125.9	202.6	1932	—	Travels north-south within the Piedmont area, connecting the cities of Greenwood and Spartanburg.
276 US 276	North Carolina state line near Cleveland	Mauldin	34.2	55.0	1932	—	Shortest US Highway in the state, going east-west; it goes through the city of Greenville.
278 US 278	Georgia state line near North Augusta	Hilton Head Island	146.0	235.0	1965	—	Travels east-west, connecting the cities of North Augusta and Hilton Head Island.
301 US 301	Georgia state line near Allendale	North Carolina state line near Dillon	190.3	306.3	1932	—	Travels north-south, loosely parallel to I-95. It connects the cities of Orangeburg, Florence, and Dillon.
321 US 321	Hardeeville	North Carolina state line near Clover	227.4	366.0	1930	—	Travels north-south, connecting the cities of Hardeeville, Columbia, and York.
378 US 378	Georgia state line near McCormick	Conway	210.9	339.4	1952	—	Travels east-west, connecting the cities of Columbia, Sumter, and Conway.
401 US 401	Sumter	North Carolina state line near McColl	77.2	124.2	1957	—	Travels north-south, connecting the cities of Sumter, Darlington, and Bennettsville.
501 US 501	Myrtle Beach	North Carolina state line near Dillon	74.0	119.1	1935	—	Travels north-south through the Grand Strand area, connecting the cities of Myrtle Beach, Conway, and Dillon.
521 US 521	Georgetown	North Carolina state line at Indian Land	173.5	279.2	1932	—	Travels north-south, connecting the cities of Georgetown, Sumter, Camden, and Lexington.
601 US 601	Tarboro	North Carolina state line at Pageland	181.4	291.9	1927	—	Travels north-south,connecting the cities of Bamberg, Orangeburg, Camden, and Pageland.
701 US 701	Georgetown	North Carolina state line near Loris	61.5	99.0	1932	—	Travels north-south through the Grand Strand area, connecting the cities of Georgetown and Conway.

Alternate routes

Route	Southern or western terminus	Northern or eastern terminus	mi	km	Established	Deleted	Description
015A1 US 15 ALT	Walterboro	North Carolina state line near McColl	0	0.0	1937	1946	The entire route was in concurrency with US 15 in South Carolina.
015A2 US 15 ALT	Sumter	Society Hill	0	0.0	1955	1957	Replaced by US 401.
017A1 US 17 ALT	Georgia state line near Savannah, Georgia	Limehouse	6.7	10.8	1955	1994	Provided an alternate route from Savannah, via the Talmadge Memorial Bridge. Was reassigned as mainline US 17.
017A2 US 17 ALT	Pocotaligo	Georgetown	123.4	198.6	1952	—	Travels north-south,connecting the cities of Walterboro, Summerville, Moncks Corner and Georgetown.
029A1 US 29 ALT	Greenville		0	0.0	1938	1948	Was an alternate route through downtown Greenville, was downgraded to secondary roads.
029A2 US 29 ALT	Spartanburg	Blacksburg	0	0.0	1955	1962	Was a rebanner of mainline US 29 between Spartanburg and Blacksburg; after I-85 was established, it was reverted to US 29.
123B1 US 123 ALT	Greenville		0	0.0	1950	1972	Replaced by SC 124.
176A1 US 176 ALT	Spartanburg		0	0.0	1938	1948	Traversed in downtown Spartanburg, along Magnolia and Howard streets. Some map inserts of the time list it as "Optional US 176;" was downgraded to secondary roads.
221A1 US 221 ALT	Chesnee	North Carolina state line near Cowpens National Battlefield	5.3	8.5	1941	—	Provides an alternate route from Chesnee to Forest City, NC.

Business loops

Route	Southern or western terminus	Northern or eastern terminus	mi	km	Established	Deleted	Description
015B1 US 15 BUS	Hartsville		6.6	10.6	1969	—	Routed along Fifth Street.
015B2 US 15 BUS	Bennettsville		0	0.0	1952	1990	Was routed along Main Street and Tyson Avenue, in concurrency with US 401 Bus. It was replaced by SC 385.
017B1 US 17 BUS	Mount Pleasant		4.2	6.8	1967	1992	Was routed along Coleman Boulevard and Georgetown Highway (Chuck Dawley Boulevard) in concurrency with US 701 Bus. It was replaced by SC 703 and BS 526.
017B2 US 17 BUS	Murrells Inlet	Myrtle Beach	22.8	36.7	1967	—	Connects the downtown areas of Murrells Inlet, Garden City, Surfside Beach and Myrtle Beach.
021B1 US 21 BUS	Beaufort		3.2	5.1	1967	—	Routed along Sea Island Parkway, Carteret Street and Boundary Street.
021B2 US 21 BUS	Orangeburg		3.3	5.3	1950	1967	Was routed along Broughton Street (in concurrency with US 178 BUS) and Columbia Road.
021B3 US 21 BUS	Orangeburg		2.9	4.7	1967	—	Routed along Rowesville Road, Charleston Highway and Magnolia Street.
021B4 US 21 BUS	Rock Hill		6.7	10.8	1950	2013	Was routed along Main Street, Albright Road, Black Street, Oakland Avenue, and Cherry Road, through downtown Rock Hill. It was decommissioned at the request of Rock Hill to gain ownership and maintenance oversight.^[2]^[3]
021B5 US 21 BUS	Fort Mill		6.1	9.8	1948	—	It is routed along Spratt Street, White Street, Old Nations Road, and Springfield Parkway, through downtown Fort Mill.
025B1 US 25 BUS	Georgia state line in North Augusta		2.8	4.5	1961	—	Only business loop that crosses the Georgia-South Carolina state line.
025B2 US 25 BUS	Greenwood		2.8	4.5	1969	—	Notes.
025B3 US 25 BUS	Ware Shoals		4.5	7.2	1963	—	Notes.
025B4 US 25 BUS	Greenville		0	0.0	1969	1995	Former business loop through downtown Greenville; replaced in parts by US 123, US 276, SC 20 and SC 291.
029B1 US 29 BUS	Anderson		6.4	10.3	1947	—	Notes.
029B2 US 29 BUS	Greenville		0	0.0	1958	1962	Notes.
052B1 US 52 BUS	Darlington		4.0	6.4	1974	—	Notes.
076B1 US 76 BUS	Seneca		0	0.0	1958	2000	Notes.
076B2 US 76 BUS	Laurens		3.8	6.1	1982	—	Notes.
076B3 US 76 BUS	Newberry		0	0.0	1952	2001	Notes.
076B4 US 76 BUS	Sumter		5.9	9.5	1959	—	Notes.
078B1 US 78 BUS	Blackville		0.7	1.1	1981	—	Notes.
123B1 US 123 BUS	Seneca		0	0.0	1958	2000	Was routed along North First Street.
123B1 US 123 BUS	Easley		0	0.0	1958	1964	Was routed along Main Street and Liberty Drive. It was replaced by SC 93.
176B1 US 176 BUS	Union		0	0.0	1958	1990	Was routed along Pinckney Street and Thompson Boulevard. It was replaced by SC 18.
178B1 US 178 BUS	Greenwood		3.9	6.3	1949	—	Notes.
178B2 US 178 BUS	Orangeburg		4.9	7.9	1970	—	Notes.
276B1 US 276 BUS	Greenville		0	0.0	1948	1970	Notes.
278B1 US 278 BUS	Hilton Head		8.8	14.2	1998	—	Notes.
321B1 US 321 BUS	Winnsboro		4.3	6.9	1952	—	Notes.
321B2 US 321 BUS	Chester		3.0	4.8	1964	—	Notes.
321B3 US 321 BUS	Chester		2.6	4.2	1958	—	Notes.
378B1 US 378 BUS	Sumter		6.6	10.6	1961	N/A	Was routed along Broad Street, Liberty Street and Myrtle Beach Boulevard.
378B2 US 378 BUS	Lake City		2.6	4.2	1958	—	Routed along Main Street (with SC 341) and Church Street/Myrtle Beach Highway.
401B1 US 401 BUS	Bennettsville		0	0.0	1958	1990	Was routed along Main Street and Tyson Avenue, in concurrency with US 15 Bus. It was replaced by SC 385.
501B1 US 501 BUS	Conway		4.4	7.1	1964	—	Notes.
501B2 US 501 BUS	Marion		6.6	10.6	1964	—	Notes.
521B1 US 521 BUS	Kershaw		1.4	2.3	N/A	—	Notes.
521B2 US 521 BUS	Lancaster		3.8	6.1	1965	—	Notes.
701B1 US 701 BUS	Mount Pleasant		4.2	6.8	1967	1992	Was routed along Coleman Boulevard and Georgetown Highway (Chuck Dawley Boulevard) in concurrency with US 17 Bus. It was replaced by SC 703 and BS 526.
701B2 US 701 BUS	North Carolina state line near Tabor City, North Carolina		0.1	0.2	1960	—	Only business loop that crosses the North-South Carolina state line.

References

↑ United States System of Highways Adopted for Uniform Marking by the American Association of State Highway Officials (Map). 1:7,000,000. Cartography by U.S. Geological Survey. Bureau of Public Roads. November 11, 1926. OCLC 32889555. Retrieved November 7, 2013.
↑ "Binder-all applications May 2013" (PDF). AASHTO. May 2013. p. 301. Retrieved July 7, 2013.
↑ "Report to SCOH from USRN SM2013 May 3" (PDF). AASHTO. May 3, 2013. p. 8. Retrieved July 7, 2013.

External links

Media related to U.S. Highways in South Carolina at Wikimedia Commons

State of South Carolina

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Regions	Atlantic Coastal Plain Blue Ridge Mountains Grand Strand High Hills of Santee Lake Murray Country Lowcountry Metrolina Midlands Ninety-Six District Olde English District Pee Dee Piedmont Sandhills Sea Islands Upstate

Larger cities	Charleston Columbia Greenville North Charleston Rock Hill Spartanburg

Smaller cities	Aiken Anderson Beaufort Bennettsville Camden Cayce Conway Easley Florence Forest Acres Gaffney Georgetown Greenwood Greer Goose Creek Hilton Head Island Isle of Palms Laurens Lexington Mauldin Myrtle Beach North Augusta North Myrtle Beach Orangeburg Simpsonville Summerville Sumter Union Walterboro West Columbia York

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CDPs	Berea Carolina Forest Dentsville Gantt Garden City Ladson Parker Red Hill Saint Andrews Seven Oaks Socastee Taylors Wade Hampton

Counties	Abbeville Aiken Allendale Anderson Bamberg Barnwell Beaufort Berkeley Calhoun Charleston Cherokee Chester Chesterfield Clarendon Colleton Darlington Dillon Dorchester Edgefield Fairfield Florence Georgetown Greenville Greenwood Hampton Horry Jasper Kershaw Lancaster Laurens Lee Lexington Marion Marlboro McCormick Newberry Oconee Orangeburg Pickens Richland Saluda Spartanburg Sumter Union Williamsburg York

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