List of protein secondary structure prediction programs
List of protein secondary structure prediction programs
| Name | Method description | Type | Link | Initial release |
|---|---|---|---|---|
| SPIDER2 | The most comprehensive and accurate prediction by iterative Deep Neural Network (DNN) for protein structural properties including secondary structure, local backbone angles, and accessible surface area (ASA) | Webserver/downloadable | server/download | 2015 |
| s2D | Predicts disorder and secondary structure in one unified framework. Trained on solution-based NMR data. | Webserver/downloadable | server/download | 2015 |
| RaptorX-SS8 | predict both 3-state and 8-state secondary structure using conditional neural fields from PSI-BLAST profiles | Webserver/downloadable | server download | 2011 |
| NetSurfP | Profile-based neural network | Webserver/downloadable | server | 2009 |
| GOR | Information theory/Bayesian inference | Many implementations | Basic GOR GOR V | 2002 (GOR V) |
| Jpred | Neural network assignment | Webserver | server | 1998 |
| Meta-PP | Consensus prediction of other servers | Webserver | server | 1999 |
| PREDATOR | Knowledge-based database comparison | Webserver | server | 1997 |
| PredictProtein | Profile-based neural network | Webserver | server | 1992 |
| PSIPRED | two feed-forward neural networks which perform an analysis on output obtained from PSI-BLAST | Webserver | server | 1999 |
| SymPred | an improved dictionary based approach which captures local sequence similarities in a group of proteins | Webserver | server | 2004 |
| YASSPP | Cascaded SVM-based predictor using PSI-BLAST profiles | Webserver | server | 2006 |
| PSSpred | Multiple backpropagation neural network predictors from PSI-BLAST profiles | Webserver/downloadable program | server and downloadable program | 2012 |
| HCAM | Hidropathy Clustering Assisted Method by detection of physicochemical patterns | downloadable program plus database | main page | 2013 |
| Frag1D | Prediction of both secondary structure and Shape Strings (discrete states of dihedral angles) using profile based fragment matching | Webserver/downloadable program | main page | 2010 |
See also
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