List of side effects of aripiprazole

The rates of adverse effect effects of aripiprazole is:[1][2][3][4][5]

Adults

Very Common (>10% incidence)

  • Weight gain
  • Headache
  • Agitation
  • Insomnia
  • Anxiety
  • Nausea & vomiting
  • Akathisia — a sense of unease and restlessness that presents itself with anxiety
  • Lightheadedness
  • Constipation

Common (1-10% incidence)

  • Dizziness
  • Dyspepsia — indigestion
  • Somnolence — which is usually mild and transient and less severe than that seen with most antipsychotics.[6]
  • Fatigue
  • Restlessness
  • Dry mouth
  • Extrapyramidal side effects (e.g. dystonia, parkinsonism, tremor, etc.)
  • Orthostatic hypotension
  • Musculoskeletal stiffness
  • Abdominal discomfort
  • Blurred vision
  • Cough
  • Pain
  • Myalgia
  • Rash
  • Rhinitis

Uncommon (0.1-1% incidence)

Rare (<0.1%)

Sudden unexplained death has been reported, however the frequency is unknown.[11]

Common in children

References

  1. "Product Information for ABILIFYTM Aripiprazole Tablets & Orally Disintegrating Tablets". TGA eBusiness Services. Bristol-Myers Squibb Australia Pty Ltd. 1 November 2012. Retrieved 22 October 2013.
  2. "ABILIFY (aripiprazole) tablet ABILIFY (aripiprazole) solution ABILIFY DISCMELT (aripiprazole) tablet, orally disintegrating ABILIFY (aripiprazole) injection, solution [Otsuka America Pharmaceutical, Inc.]". DailyMed. Otsuka America Pharmaceutical, Inc. April 2013. Retrieved 22 October 2013.
  3. "Abilify Tablets, Orodispersible Tablets, Oral Solution - Summary of Product Characteristics (SPC)". electronic Medicines Compendium. Otsuka Pharmaceuticals (UK) Ltd. 20 September 2013. Retrieved 22 October 2013.
  4. "ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS" (PDF). European Medicines Agency. Otsuka Pharmaceutical Europe Ltd. Retrieved 22 October 2013.
  5. "Abilify Discmelt, Abilify Maintena (aripiprazole) dosing, indications, interactions, adverse effects, and more". Medscape Reference. WebMD. Retrieved 22 October 2013.
  6. 1 2 Leucht S, Cipriani A, Spineli L, Mavridis D, Orey D, Richter F, Samara M, Barbui C, Engel RR, Geddes JR, Kissling W, Stapf MP, Lässig B, Salanti G, Davis JM (September 2013). "Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis.". Lancet 382 (9896): 951–962. doi:10.1016/S0140-6736(13)60733-3. PMID 23810019.
  7. 1 2 "ABILIFY (aripiprazole) [package insert]." (PDF). Otsuka Pharmaceutical Co, Ltd. Retrieved 18 October 2012.
  8. Abbasian C, Power P (March 2009). "A case of aripiprazole and tardive dyskinesia". J Psychopharmacol (Oxford) 23 (2): 214–5. doi:10.1177/0269881108089591. PMID 18515468.
  9. Zaidi SH, Faruqui RA (January 2008). "Aripiprazole is associated with early onset of Tardive Dyskinesia like presentation in a patient with ABI and psychosis". Brain Inj 22 (1): 99–102. doi:10.1080/02699050701822493. PMID 18183513.
  10. Maytal G, Ostacher M, Stern TA (June 2006). "Aripiprazole-related tardive dyskinesia". CNS Spectr 11 (6): 435–9. PMID 16816781.
  11. http://www.medicines.org.uk/EMC/pdfviewer.aspx?isAttachment=true&documentid=16161
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