Lloyd M. Smith

For the Australian cricketer, see Lloyd Smith (cricketer).
Lloyd M. Smith

Lloyd M. Smith
Born (1954-10-03)October 3, 1954
Citizenship American
Fields Biochemistry
Institutions University of Wisconsin-Madison
Alma mater University of California, Berkeley
Doctoral advisor Harden M. McConnell
Known for DNA sequencing

Lloyd M. Smith PhD. (born October 3, 1954) is a professor of chemistry and the founder of Third Wave Technologies.

Early life

Smith spent his formative years in Berkeley, California, where his parents worked as professors of physics and mathematics. He majored in Biochemistry at the University of California in 1976, performing research with Wayne Hubbell, and subsequently obtained his PhD from Stanford University for his work on membrane diffusion with Harden M. McConnell.[1][2]

Career

In 1982 Smith did post-doctorate work with Leroy Hood at the California Institute of Technology, where he created the world's first fluorescence-based automated DNA sequencing instrument.[1][3][4] During the early 80s he also worked as a consultant for Applied Biosystems, who were able to commercialise the sequencing process he developed and bring it to market. This sequencing process was to have a direct effect on the development of the Human Genome Project.[5]

In 1987, Smith joined the University of Wisconsin–Madison as an assistant professor; he subsequently held posts there as Chair of the Analytical Sciences Division and Director of the University's Genome Center.[1] He has held posts on the boards of Visible Genetics, GWC Technologies, and founded Third Wave Technologies and Gentel BioSciences.[3]

Academic research and publications

Smith has authored or co-authored over 250 papers. He holds over 30 U.S. patents for his inventions in the field of biochemistry.[6] He held the John D. MacArthur Chair in Chemistry at Wisconsin-Madison, and is currently the W. L. Hubbell Professor of Chemistry there.[2][7]

He was listed as one of the Top 100 Innovators by Science Digest, has won a Presidential Young Investigator Award, and has received an Eli Lilly Analytical Chemistry Award. His work on automated DNA sequencing won the Association of Biomolecular Resource Facilities Award in 1997.[3]

References

  1. 1 2 3 Brock, David C.; Ulrych, Richard. "Lloyd M. Smith". Chemical Heritage Foundation. Retrieved 20 October 2014.
  2. 1 2 Lederman, Lynne (Nov 2007). "Profile of Lloyd M. Smith". BioTechniques 43 (5): 549. doi:10.2144/000112603. Retrieved 20 October 2014.
  3. 1 2 3 "Executive profile: Lloyd M. Smith". Bloomberg Businessweek. Retrieved 20 October 2014.
  4. Maher, Brendan. "The First Automated DNA Sequencer". The Scientist. Retrieved 20 October 2014.
  5. Cook-Deegan, Robert Mullan. "Origins of the Human Genome Project". University of Washington. Retrieved 20 October 2014.
  6. "Patents by Inventor Lloyd M. Smith". Justia patents. Justia. Retrieved 23 October 2014.
  7. "Lloyd M. Smith". Department of Chemistry. University of Wisconsin-Madison. Retrieved 22 October 2014.
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