Long-chain acyl-(acyl-carrier-protein) reductase

Long-chain acyl-(acyl-carrier-protein) reductase (EC 1.2.1.80, long-chain acyl-[acp] reductase, fatty acyl-[acyl-carrier-protein] reductase, acyl-[acp] reductase) is an enzyme with systematic name long-chain-aldehyde:NAD(P)⁺ oxidoreductase (acyl-(acyl-carrier protein)-forming).^[1] This enzyme catalyses the following chemical reaction

a long-chain aldehyde + acyl-carrier protein + NAD(P)+

\rightleftharpoons

a long-chain acyl-[acyl-carrier protein] + NAD(P)H + H⁺

This enzyme catalyses the reaction in the opposite direction.

References

↑ Schirmer, A., Rude, M.A., Li, X., Popova, E. and del Cardayre, S.B. (2010). "Microbial biosynthesis of alkanes". Science 329 (5991): 559–562. doi:10.1126/science.1187936. PMID 20671186.

External links

Long-chain acyl-(acyl-carrier-protein) reductase at the US National Library of Medicine Medical Subject Headings (MeSH)

Aldehyde/oxo oxidoreductases (EC 1.2)

1.2.1: NAD or NADP	Aldehyde dehydrogenase Acetaldehyde dehydrogenase Long-chain-aldehyde dehydrogenase

1.2.2: cytochrome	Formate dehydrogenase (cytochrome)

1.2.3: oxygen	Aldehyde oxidase

1.2.4: disulfide	Oxoglutarate dehydrogenase complex Pyruvate dehydrogenase Branched-chain alpha-keto acid dehydrogenase complex BCKDHA BCKDHB DBT DLD

1.2.7: iron-sulfur protein	Pyruvate synthase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

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