Low-grade fibromyxoid sarcoma

Low-grade fibromyxoid sarcoma
Micrograph of a low-grade fibromyxoid sarcoma. H&E stain.
Classification and external resources

Low-grade fibromyxoid sarcoma (LGFMS) is a rare type of low grade sarcoma first described by Harry Evans in 1987. It is characterized by a long and indolent clinical course and the possibility of local recurrence or distant metastases in a subset of patients. Unlike many other types of cancer, low grade fibromyxoid sarcoma can metastasize after many years, sometimes decades after the initial presentation of the tumor.^[1]

References

1. Evans, Harry L (2011). "Low-Grade Fibromyxoid Sarcoma: A Clinicopathologic Study of 33 Cases With Long-Term Follow-Up". The American Journal of Surgical Pathology 35 (10): 1450–1462. doi:10.1097/PAS.0b013e31822b3687. PMID 21921785.

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• Panagopoulos I, Möller E, Dahlén A, Dahlén A, Isaksson M, Mandahl N, Vlamis-Gardikas A, Mertens F: Characterization of the native CREB3L2 transcription factor and the FUS/CREB3L2 chimera. Genes Chromosomes Cancer 2007, 46(2):181-91.