MAN1B1

Mannosidase, alpha, class 1B, member 1

PDB rendering based on 1fmi.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols MAN1B1 ; ERMAN1; MANA-ER; MRT15
External IDs OMIM: 604346 MGI: 2684954 HomoloGene: 5230 ChEMBL: 2308 GeneCards: MAN1B1 Gene
EC number 3.2.1.113
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 11253 227619
Ensembl ENSG00000177239 ENSMUSG00000036646
UniProt Q9UKM7 A2AJ15
RefSeq (mRNA) NM_016219 NM_001029983
RefSeq (protein) NP_057303 NP_001025154
Location (UCSC) Chr 9:
137.09 – 137.11 Mb
Chr 2:
25.33 – 25.35 Mb
PubMed search

Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase is an enzyme that in humans is encoded by the MAN1B1 gene.[1][2][3]

References

  1. Gonzalez DS, Karaveg K, Vandersall-Nairn AS, Lal A, Moremen KW (Aug 1999). "Identification, expression, and characterization of a cDNA encoding human endoplasmic reticulum mannosidase I, the enzyme that catalyzes the first mannose trimming step in mammalian Asn-linked oligosaccharide biosynthesis". J Biol Chem 274 (30): 21375–86. doi:10.1074/jbc.274.30.21375. PMID 10409699.
  2. Tremblay LO, Herscovics A (Nov 1999). "Cloning and expression of a specific human alpha 1,2-mannosidase that trims Man9GlcNAc2 to Man8GlcNAc2 isomer B during N-glycan biosynthesis". Glycobiology 9 (10): 1073–8. doi:10.1093/glycob/9.10.1073. PMID 10521544.
  3. "Entrez Gene: MAN1B1 mannosidase, alpha, class 1B, member 1".

Further reading

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