MARVELD2

MARVEL domain containing 2
Identifiers
Symbols	MARVELD2 ; DFNB49; MARVD2; MRVLDC2; Tric
External IDs	OMIM: 610572 MGI: 2446166 HomoloGene: 27037 GeneCards: MARVELD2 Gene
Gene ontology Molecular function • protein binding Cellular component • cytoplasm • bicellular tight junction • integral component of membrane • basolateral plasma membrane • apical plasma membrane • cytoplasmic vesicle • paranodal junction • Schmidt-Lanterman incisure Biological process • sensory perception of sound • cell-cell junction organization • establishment of endothelial barrier • bicellular tight junction assembly Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	153562	218518
Ensembl	ENSG00000152939	ENSMUSG00000021636
UniProt	Q8N4S9	Q3UZP0
RefSeq (mRNA)	NM_001038603	NM_001038602
RefSeq (protein)	NP_001033692	NP_001033691
Location (UCSC)	Chr 5: 69.42 – 69.44 Mb	Chr 13: 100.6 – 100.62 Mb
PubMed search

MARVEL domain-containing protein 2 is a protein that in humans is encoded by the MARVELD2 gene.^[1][2]

References

1. Riazuddin S, Ahmed ZM, Fanning AS, Lagziel A, Kitajiri S, Ramzan K, Khan SN, Chattaraj P, Friedman PL, Anderson JM, Belyantseva IA, Forge A, Riazuddin S, Friedman TB (Dec 2006). "Tricellulin is a tight-junction protein necessary for hearing". Am J Hum Genet 79 (6): 1040–51. doi:10.1086/510022. PMC 1698716. PMID 17186462.
2. "Entrez Gene: MARVELD2 MARVEL domain containing 2".

Further reading

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
• Ikenouchi J, Furuse M, Furuse K, et al. (2006). "Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells.". J. Cell Biol. 171 (6): 939–45. doi:10.1083/jcb.200510043. PMC 2171318. PMID 16365161.
• Zhang Y, Wolf-Yadlin A, Ross PL, et al. (2005). "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules.". Mol. Cell Proteomics 4 (9): 1240–50. doi:10.1074/mcp.M500089-MCP200. PMID 15951569.
• Ramzan K, Shaikh RS, Ahmad J, et al. (2005). "A new locus for nonsyndromic deafness DFNB49 maps to chromosome 5q12.3-q14.1.". Hum. Genet. 116 (1-2): 17–22. doi:10.1007/s00439-004-1205-8. PMID 15538632.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.