MEG8

Maternally expressed 8 (non-protein coding)
Identifiers
Symbols	MEG8 ; Bsr; Irm; LINC00024; NCRNA00024; Rian
External IDs	OMIM: 613648 GeneCards: MEG8 Gene
Gene ontology
Orthologs
Species	Human	Mouse
Entrez	79104	n/a
Ensembl	ENSG00000258399	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	Chr 14: 100.89 – 100.94 Mb	n/a
PubMed search		n/a

In molecular biology, Maternally expressed 8 (non-protein coding), also known as MEG8 or Rian (RNA Imprinted and Accumulated in Nucleus), is a long non-coding RNA. It is an imprinted gene, which is maternally expressed. It is expressed in the nucleus and (in an eight-week-old sheep) is preferentially expressed in skeletal muscle.^[1][2]

See also

• Long noncoding RNA

References

1. Hatada I, Morita S, Obata Y, Sotomaru Y, Shimoda M, Kono T (2001). "Identification of a new imprinted gene, Rian, on mouse chromosome 12 by fluorescent differential display screening.". J Biochem 130 (2): 187–90. doi:10.1093/oxfordjournals.jbchem.a002971. PMID 11481034.
2. Charlier C, Segers K, Wagenaar D, Karim L, Berghmans S, Jaillon O, et al. (2001). "Human-ovine comparative sequencing of a 250-kb imprinted domain encompassing the callipyge (clpg) locus and identification of six imprinted transcripts: DLK1, DAT, GTL2, PEG11, antiPEG11, and MEG8.". Genome Res 11 (5): 850–62. doi:10.1101/gr.172701. PMC 311092. PMID 11337479.

Further reading

• Cavaillé J, Seitz H, Paulsen M, Ferguson-Smith AC, Bachellerie JP (2002). "Identification of tandemly-repeated C/D snoRNA genes at the imprinted human 14q32 domain reminiscent of those at the Prader-Willi/Angelman syndrome region.". Hum Mol Genet 11 (13): 1527–38. doi:10.1093/hmg/11.13.1527. PMID 12045206.