MPHOSPH8

M-phase phosphoprotein 8
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 3LWE​, 3QO2​, 3R93​, 3SVM​
Identifiers
Symbols	MPHOSPH8 ; HSMPP8; TWA3; mpp8
External IDs	OMIM: 611626 MGI: 1922589 HomoloGene: 11380 ChEMBL: 1741210 GeneCards: MPHOSPH8 Gene
EC number	2.4.2.30
Gene ontology Molecular function • protein binding • methylated histone binding Cellular component • nuclear nucleosome • nucleus • nucleoplasm • nuclear heterochromatin • nucleolus • cytoplasm • plasma membrane • extracellular exosome Biological process • transcription, DNA-templated • regulation of DNA methylation • negative regulation of transcription, DNA-templated Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	54737	75339
Ensembl	ENSG00000196199	ENSMUSG00000079184
UniProt	Q99549	Q3TYA6
RefSeq (mRNA)	NM_017520	NM_023773
RefSeq (protein)	NP_059990	NP_076262
Location (UCSC)	Chr 13: 19.63 – 19.67 Mb	Chr 14: 56.67 – 56.7 Mb
PubMed search

M-phase phosphoprotein 8 is an enzyme that in humans is encoded by the MPHOSPH8 gene.^[1][2]

References

1. Matsumoto-Taniura N, Pirollet F, Monroe R, Gerace L, Westendorf JM (Jan 1997). "Identification of novel M phase phosphoproteins by expression cloning". Mol Biol Cell 7 (9): 1455–69. doi:10.1091/mbc.7.9.1455. PMC 275994. PMID 8885239.
2. "Entrez Gene: HSMPP8 M-phase phosphoprotein, mpp8".

Further reading

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
• Maksimov VV, Arman IP, Tarantul VZ (2006). "[Identification of the proteins interacting with neuroprotective peptide humanin in a yeast two-hybrid system]". Genetika 42 (2): 274–7. PMID 16583711.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13.". Nature 428 (6982): 522–8. doi:10.1038/nature02379. PMC 2665288. PMID 15057823.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Umeda M, Nishitani H, Nishimoto T (2003). "A novel nuclear protein, Twa1, and Muskelin comprise a complex with RanBPM.". Gene 303: 47–54. doi:10.1016/S0378-1119(02)01153-8. PMID 12559565.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.