MSFS

MSFS may refer to:

• Master of Science in Foreign Service, a graduate degree awarded by the Edmund A. Walsh School of Foreign Service at Georgetown University, Washington, D.C and by the FEPAC accredited Forensic Science Graduate Program at Marshall University, Huntington, WV.
• Microsoft Flight Simulator, a simulation of dynamic flight.
• Missionaries of St. Francis de Sales, a Catholic religious group founded in response to the desire of St. Francis de Sales to found a society of missionary priests.