Medronic acid

Not to be confused with mildronate or minodronate.
Medronic acid
Names
IUPAC name
methanediylbis(phosphonic acid)
Other names
methanediphosphonic acid; methylenebis(phosphonic acid); methylene diphosphonate; medronate; phosphonomethylphosphonic acid; MDP
Identifiers
1984-15-2 N
ChEBI CHEBI:43945 N
ChEMBL ChEMBL180570 YesY
ChemSpider 15308 YesY
Jmol interactive 3D Image
KEGG D04887 YesY
PubChem 16124
UNII 73OS0QIN3O N
Properties
CH6O6P2
Molar mass 176.00 g·mol−1
Melting point 199 to 200 °C (390 to 392 °F; 472 to 473 K)[1]
Hazards
Lethal dose or concentration (LD, LC):
45-50 mg/kg (i.v., mice, rabbits)[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Medronic acid (conjugate base, medronate) is the smallest bisphosphonate. Its complex with radioactive technetium, 99mTc medronic acid, is used in nuclear medicine to detect bone abnormalities, including metastases.

References

  1. 1 2 Budavari, Susan, ed. (1996), The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals (12th ed.), Merck, ISBN 0911910123


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