Metopimazine

Metopimazine
Systematic (IUPAC) name

1-(3-[2-(methylsulfonyl)-10H-phenothiazin-10-yl]propyl)piperidine-4-carboxamide
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Number	14008-44-7^N
ATC code	A04AD05 (WHO)
PubChem	CID 26388
ChemSpider	24584^Y
UNII	238S75V9AV^Y
ChEMBL	CHEMBL398615^Y
Chemical data
Formula	C₂₂H₂₇N₃O₃S₂
Molar mass	445.6 g/mol
SMILES O=S(=O)(c2cc1N(c3c(Sc1cc2)cccc3)CCCN4CCC(C(=O)N)CC4)C
InChI InChI=1S/C22H27N3O3S2/c1-30(27,28)17-7-8-21-19(15-17)25(18-5-2-3-6-20(18)29-21)12-4-11-24-13-9-16(10-14-24)22(23)26/h2-3,5-8,15-16H,4,9-14H2,1H3,(H2,23,26)^Y Key:BQDBKDMTIJBJLA-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)

Metopimazine (INN) is a phenothiazine antiemetic.

References

Antiemetics (A04)

5-HT3 Serotonin ion channel antagonists	Alosetron Azasetron Bemesetron Cilansetron Clozapine Dazopride Dolasetron Granisetron Lerisetron Metoclopramide Mianserin Mirtazapine Olanzapine Ondansetron Palonosetron Quetiapine Ramosetron Ricasetron Tropisetron Zatosetron

5-HT Serotonin G-protein receptor antagonists	Clozapine Cyproheptadine Hydroxyzine Olanzapine Risperidone Ziprasidone

CB₁ Agonists (Cannabinoids)	Dronabinol Nabilone Tetrahydrocannabinol (cannabis)

D₂/D₃ Antagonists	Alizapride Bromopride Chlorpromazine Clebopride Domperidone Haloperidol Hydroxyzine Itopride Metoclopramide Metopimazine Prochlorperazine Thiethylperazine

H₁ antagonists (Antihistamines)	Cyclizine Dimenhydrinate Diphenhydramine Hydroxyzine Meclozine Promethazine

mACh antagonists (Anticholinergics)	Atropine Diphenhydramine Hydroxyzine (very mild) Hyoscyamine Scopolamine

NK₁ Antagonists	Aprepitant Casopitant Ezlopitant Fosaprepitant Maropitant Netupitant Rolapitant Vestipitant

Others	Cerium oxalate Dexamethasone Lorazepam Midazolam Propofol Trimethobenzamide

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