Michael Elowitz

Michael Elowitz
Nationality American
Fields Biology
Institutions California Institute of Technology;
Howard Hughes Medical Institute
Alma mater University of California, Berkeley
Notable awards MacArthur Fellows Program

Michael B. Elowitz is a biologist and professor of Biology, Bioengineering, and Applied Physics at the California Institute of Technology,[1][2][3] and investigator at the Howard Hughes Medical Institute.[4] In 2007 he was the recipient of the Genius grant, better known as the MacArthur Fellows Program for the design of a synthetic gene regulatory network, the Repressilator, which helped initiate the field of synthetic biology.[5] In addition, he showed, for the first time, how inherently random effects, or 'noise', in gene expression could be detected and quantified in living cells,[6] leading to a growing recognition of the many roles that noise plays in living cells. His work in Synthetic Biology and Noise represent two foundations of the field of Systems Biology.

Career

His laboratory studies the dynamics of genetic circuits in individual living cells using synthetic biology, time-lapse microscopy, and mathematical modeling, with a particular focus on the way in which cells make use of noise to implement behaviors that would be difficult or impossible without it. Recently, his lab has expanded their approaches beyond bacteria to include eukaryotic and mammalian cells.[7]

Life

Elowitz grew up in Los Angeles, California, where he attended the humanities magnet at Alexander Hamilton High School (Los Angeles). He studied Physics and graduated with a B.A. from the University of California, Berkeley in 1992,[8] and from Princeton University with a Ph.D. in 1999.[9] In 1997-1998, he spent one year at the European Molecular Biology Laboratory at Heidelberg. Afterwards, he was a postdoctoral fellow at the Rockefeller University in New York City.

While working as a graduate student at Princeton he co-authored songs such as Sunday at the Lab[10] with Uri Alon.

Awards

Peer-reviewed publications

References

  1. ↑ http://www.elowitz.caltech.edu/people.html
  2. ↑ http://biology.caltech.edu/Members/Elowitz
  3. ↑ http://www.aph.caltech.edu/people/elowitz_m.html
  4. ↑ http://www.hhmi.org/news/elowitz_bio.html
  5. ↑ http://www.nature.com/nature/journal/v463/n7279/full/463269b.html
  6. ↑ http://stke.sciencemag.org/cgi/content/abstract/sci;297/5584/1183
  7. ↑ "Gene Circuit Dynamics in Regulation and Differentiation", Howard Hughes Medical Institute
  8. ↑ Applied Physics at Cal Tech, retrieved 9 March 2010
  9. ↑ http://www.searlescholars.net/go.php?id=27
  10. ↑ http://www.youtube.com/watch?v=yhncg6GXYq8 Sunday at the Lab performed by Uri Alon
  11. ↑ http://www.hfsp.org/awardees/hfsp-nakasone-award/2011-award
  12. ↑ Presidential Early Career Award for Scientists and Engineers
  13. ↑ http://discovermagazine.com/2008/dec/20-best-brains-under-40#.UT7ErKUZ6Rg
  14. ↑ http://www.macfound.org/site/c.lkLXJ8MQKrH/b.2913825/apps/nl/content2.asp?content_id={B319FBF7-A99D-48DB-9293-3CF3434EC3C2}&notoc=1
  15. ↑ http://www.packard.org/what-we-fund/conservation-and-science/packard-fellowships-for-science-and-engineering/fellowship-directory/elowitz-michael/
  16. ↑ Category:TR35 winners
  17. ↑ https://forms.bwfund.org/news/awardee_profiles/michael_elowitz.html
  18. ↑ Bintu, Lacramioara; Yong, John; Antebi, Yaron E.; McCue, Kayla; Kazuki, Yasuhiro; Uno, Narumi; Oshimura, Mitsuo; Elowitz, Michael B. (2016-02-12). "Dynamics of epigenetic regulation at the single-cell level". Science 351 (6274): 720–724. doi:10.1126/science.aab2956. ISSN 0036-8075.
  19. ↑ Lin, Yihan; Sohn, Chang Ho; Dalal, Chiraj K.; Cai, Long; Elowitz, Michael B. "Combinatorial gene regulation by modulation of relative pulse timing". Nature 527: 54–58. doi:10.1038/nature15710.

External links

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