Mitochondrial tRNA pseudouridine27/28 synthase

Mitochondrial tRNA pseudouridine^27/28 synthase (EC 5.4.99.44, Pus2, Pus2p, RNA:pseudouridine synthases 2) is an enzyme with systematic name mitochondrial tRNA-uridine^27/28 uracil mutase.^[1] This enzyme catalyses the following chemical reaction

mitochondrial tRNA uridine^27/28

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mitochondrial tRNA pseudouridine^27/28

The mitochondrial enzyme Pus2p is specific for position 27 or 28 in mitochondrial tRNA.

References

↑ Behm-Ansmant, I., Branlant, C. and Motorin, Y. (2007). "The Saccharomyces cerevisiae Pus2 protein encoded by YGL063w ORF is a mitochondrial tRNA:Ψ^27/28-synthase". RNA 13: 1641–1647. doi:10.1261/rna.605607. PMID 17684231.

External links

Mitochondrial tRNA pseudouridine27/28 synthase at the US National Library of Medicine Medical Subject Headings (MeSH)

Isomerase: mutases (EC 5.4)

5.4.1 Acyl Groups	Lysolecithin acylmutase Precorrin-8X methylmutase

5.4.2 Phosphomutases	Phosphoglycerate mutase Bisphosphoglycerate mutase Phosphoglucomutase Phosphomannomutase PMM1 PMM2

5.4.99 Other groups	Methylmalonyl-CoA mutase Lanosterol synthase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

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