Movement disorder
Movement disorders can be defined as neurologic syndromes in which either an excess or movement or a paucity of voluntary and automatic movements, unrelated to weakness or spasticity.[1] The term movement disorders is used synonymously with basal ganglia or extrapyramical diseases.[2] Conventionally movement disorders are divided into two major categories: 1. Hyperkinetic movement disorders also called dyskinesias refers to excessive, often repetitive, involuntary movements that intrude into the normal flow of motor activity. 2. Hypokinetic movement disorders refers to akinesia (lack of movement), hypokinesia (reduced amplitude of movements), bradykinesia (slow movement) and rigidity. In primary movement disorders the abnormal movement is the primary manifestation of the disorder. In secondary movement disorders it is an manifestation of other systemic or neruological disorder.[3]
History
Vesalius and Piccolomini in 16th century distinguished subcortical nuclei from cortex and white matter. However Willis' conceptualized the corpus striatum as the seat of motor power in the late 17th century. In mid-19th-century movement disorders were localized to striatum by Choreaby Broadbent and Jackson, and athetosis by Hammond. By the late 19th century, many movement disorders were described but for most no pathologic correlate was known.[4]
Classification
Approach to Diagnosis[6]
Step I : Decide the dominant type of movement disorder
Step II : Make differential diagnosis of the particular disorder
Step II: Confirm the diagnosis by lab tests
- Metabolic screening
- Microbiology
- Immunology
- CSF examination
- Genetics
- Imaging
- Neurophysiological tests
- Pharmacological tests
Treatment
Treatment depends upon the underlying disorder.[7] Movement disorders have been known to be associated with a variety of autoimmune diseases.[8]
References
- ↑ Fahn, Stanley; Jankovic, Joseph; Hallett, Mark (2011-08-09). Principles and Practice of Movement Disorders. Elsevier Health Sciences. ISBN 1437737706.
- ↑ Bradley, Walter George (2004-01-01). Neurology in Clinical Practice: Principles of diagnosis and management. Taylor & Francis. ISBN 9789997625885.
- ↑ Flemming, Kelly; Jones, Lyell (2015-06-15). Mayo Clinic Neurology Board Review: Clinical Neurology for Initial Certification and MOC. Oxford University Press. ISBN 9780190244934.
- ↑ Lanska, Douglas J. (2010-01-01). "Chapter 33: the history of movement disorders". Handbook of Clinical Neurology 95: 501–546. doi:10.1016/S0072-9752(08)02133-7. ISSN 0072-9752. PMID 19892136.
- ↑ Singer, Harvey S.; Mink, Jonathan; Gilbert, Donald L.; Jankovic, Joseph (2015-10-27). Movement Disorders in Childhood. Academic Press. ISBN 9780124115804.
- ↑ Poewe, Werner; Jankovic, Joseph (2014-02-20). Movement Disorders in Neurologic and Systemic Disease. Cambridge University Press. ISBN 9781107024618.
- ↑ "MedlinePlus: Movement Disorders".
- ↑ Baizabal-Carvallo, JF; Jankovic J. (2012-07-18). "Movement disorders in autoimmune diseases.". Movement disorders : official journal of the Movement Disorder Society Jul (8): 935–46. doi:10.1002/mds.25011. PMID 22555904. Retrieved 11 October 2013.
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| Primarily nervous system | Primarily CNS | |
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| Primarily PNS | |
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| Primarily muscular | |
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| Primarily skeletal | |
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| Primarily joint | |
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