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Investigation of potential copyright issue
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The previous content of this page or section has been identified as posing a potential copyright issue, as a copy or modification of the text from the source(s) below, and is now listed on Wikipedia:Copyright problems (listing):
- http://www.researchgate.net/publication/23281014_The_lysis_system_of_the_Streptomyces_aureofaciens_phage_16 http://tcdb.org/search/result.php?tc=1.E.28 (Duplication Detector report)
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The Streptomyces aureofaciens Phage Mu1/6 Holin (Mu1/6 Holin) Family (TC# 1.E.28) is a family of putative pore-forming holins between 80 and 90 amino acyl residues in length with 2 transmembrane segments (TMSs). A representative list of proteins belonging to this family can be found in the Transporter Classification Database.[1]
Two genes, designated, lyt and hol, are in the lysis module domain of bacteriophage mu1/6. An additional candidate holin gene, hol2, is encoded downstream from the hol gene based on one predicted transmembrane domain and a highly charged C-terminal sequence.[2] Expression of hol or hol2 in E. coli has been observed to caused cell death. Holin function was demonstrated in Streptomycetes by allowing release of mu1/6 endolysin into the periplasm. Subsequent cleavage of the peptidoglycan was observed, which suggested that the holin produces lesions in the streptomycete membrane.[2]
See also
Further reading
References
As of this edit, this article uses content from "1.E.28 The Streptomyces aureofaciens Phage Mu1/6 Holin (Mu1/6 Holin) Family", which is licensed in a way that permits reuse under the Creative Commons Attribution-ShareAlike 3.0 Unported License, but not under the GFDL. All relevant terms must be followed.
